Yoo Kwang-Ho, Kim Beom-Joon, Rho Yong-Kwan, Lee Jin-Woong, Kim Yeun-Jin, Kim Myeung-Nam, Song Kye-Yong
Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea.
Ann Dermatol. 2009 Feb;21(1):46-8. doi: 10.5021/ad.2009.21.1.46. Epub 2009 Feb 28.
A neurofibroma is a benign tumor of the peripheral nerve sheath characterized by proliferation of Schwann cells, perineural cells, and endoneurial fibroblasts. Different types of neurofibromas can be identified, including localized, plexiform, and diffuse types. Neurofibromas can involve any site on the body skin. The diffuse variant is rare and occurs primarily in children and young adults. It involves the skin and subcutaneous tissue in a plaque-like fashion on the head and neck regions. We present a case of a 10-year-old boy who had a diffuse neurofibroma on the scalp.
神经纤维瘤是一种周围神经鞘的良性肿瘤,其特征为施万细胞、神经周细胞和神经内膜成纤维细胞的增殖。可以识别出不同类型的神经纤维瘤,包括局限性、丛状和弥漫性类型。神经纤维瘤可累及身体皮肤的任何部位。弥漫性变体较为罕见,主要发生于儿童和年轻人。它以斑块样方式累及头颈部区域的皮肤和皮下组织。我们报告一例10岁男孩头皮弥漫性神经纤维瘤的病例。