Choi Kyong Min
Department of Pediatrics, Kwandong University College of Medicine, Goyang, Korea.
Korean J Pediatr. 2010 May;53(5):623-8. doi: 10.3345/kjp.2010.53.5.623. Epub 2010 May 31.
The mumps virus is a single-stranded, non-segmented, negative-sense RNA virus belonging to the Paramyxoviridae family. Mumps is characterized by bilateral or unilateral swelling of the parotid gland. Aseptic meningitis is a common complication, and orchitis is also common in adolescents and adult men. Diagnosis is based on clinical findings, but because of high vaccination coverage, clinical findings alone are not sufficient for diagnosis, and laboratory confirmation is needed. Mumps is preventable by vaccination, but despite high vaccination coverage, epidemics occur in several countries, including Korea. Many hypotheses are suggested for these phenomena. In this review, we investigate the reason for the epidemics, optimal methods of diagnosis, and surveillance of immunization status for the prevention of future epidemics.
腮腺炎病毒是一种单链、不分节段的负链RNA病毒，属于副粘病毒科。腮腺炎的特征是腮腺双侧或单侧肿大。无菌性脑膜炎是常见的并发症，睾丸炎在青少年和成年男性中也很常见。诊断基于临床表现，但由于疫苗接种覆盖率高，仅靠临床表现不足以确诊，还需要实验室确认。腮腺炎可通过接种疫苗预防，但尽管疫苗接种覆盖率高，包括韩国在内的几个国家仍有疫情发生。针对这些现象提出了许多假设。在本综述中，我们探讨了疫情发生的原因、最佳诊断方法以及免疫状况监测，以预防未来的疫情。
