Fica Alberto, Díaz María C, Aguilar Constanza, Velásquez Juan C
Hospital Base de Valdivia, Valdivia, Chile.
Escuela de Medicina, Universidad Austral de Chile, Valdivia, Chile.
Rev Chilena Infectol. 2019 Feb;36(1):106-111. doi: 10.4067/S0716-10182019000100106.
We report two cases of acute aseptic meningitis associated to mumps in middle-aged women, one pregnant. Both presented shortly after parotid gland enlargement. Neurological complications were suspected by headache, fever and meningeal signs and confirmed by CSF findings (mononuclear predominant pleocytosis) with negative results for alternative causes. Mumps were confirmed by positive IgM and IgG serology. Both patients were discharged with a favorable evolution and complete disappearance of symptoms. Cases were concurrent with a regional mumps outbreak. Conclusions: Aseptic meningitis is a rare mumps-associated neurological complication. Its diagnostic can be achieved by precedent parotid enlargement, mononuclear pleocytosis in the CSF and positive IgM and IgG serology or viral detection by PCR in urine or salivary samples. This complication would be more probably observed during mumps outbreaks.
我们报告了两例中年女性与腮腺炎相关的急性无菌性脑膜炎病例，其中一例为孕妇。两例均在腮腺肿大后不久出现。通过头痛、发热和脑膜刺激征怀疑有神经系统并发症，并通过脑脊液检查结果（以单核细胞为主的细胞增多）得到证实，排除了其他病因。腮腺炎通过IgM和IgG血清学阳性得以确诊。两名患者均康复出院，症状完全消失。这些病例与当地的腮腺炎疫情同时发生。结论：无菌性脑膜炎是一种罕见的与腮腺炎相关的神经系统并发症。其诊断可通过先前的腮腺肿大、脑脊液中的单核细胞增多以及IgM和IgG血清学阳性或通过尿液或唾液样本的PCR检测病毒来实现。这种并发症在腮腺炎疫情期间更有可能出现。
