Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-8181, USA.
Biomed Microdevices. 2011 Apr;13(2):375-81. doi: 10.1007/s10544-010-9506-2.
We present a maskless micropatterning system that utilizes a fluorescence microscope with programmable X-Y stage and dry film photoresist to realize feature sizes in the sub-millimeter range (40-700 μm). The method allows for flexible in-house maskless photolithography without a dedicated microfabrication facility and is well-suited for rapid prototyping of microfluidic channels, scaffold templates for protein/cell patterning or optically-guided cell encapsulation for biomedical applications.
我们提出了一种无掩模微图案化系统,该系统利用带有可编程 X-Y 工作台的荧光显微镜和干膜光致抗蚀剂,实现亚毫米级(40-700 μm)的特征尺寸。该方法无需专用微加工设备即可实现灵活的内部无掩模光刻,非常适合用于快速制作微流道、用于蛋白质/细胞图案化的支架模板或用于生物医学应用的光学引导细胞封装。