Tromm A, Respondek M, Schwegler U, Kuntz H D, May B
Bergmannsheil Bochum, Universitätsklinik, Abt. für Gastroenterologie und Hepatologie.
Z Gastroenterol. 1990 Apr;28(4):208-10.
We report the case of a 23-year old woman suffering from Crohn's ileocolitis for 14 years who died of a prolonged shock followed by hyperglycaemia. The post-mortem examination showed an acute pancreatitis. There was no hint for Crohn's disease of the duodenum or primary sclerosing cholangitis (PSC). Unexplained Pancreatitis coincident with Crohn's disease might be a possible extraintestinal manifestation of the disease. However such association remains speculative at the moment. Further studies based on morphological, functional, immunological and epidemiological data are required. Review of the literature and our own data show the necessity to look attentive for other causes of acute pancreatitis associated with Crohn's disease (PSC, pancreas divisum, drug induced-pancreatitis).
我们报告了一例患有克罗恩病性回结肠炎症14年的23岁女性病例，该患者死于长时间休克后继发的高血糖症。尸检显示为急性胰腺炎。未发现十二指肠克罗恩病或原发性硬化性胆管炎（PSC）的迹象。与克罗恩病同时出现的不明原因胰腺炎可能是该疾病一种可能的肠外表现。然而，目前这种关联仍具有推测性。需要基于形态学、功能学、免疫学和流行病学数据进行进一步研究。文献回顾及我们自己的数据表明，有必要仔细排查与克罗恩病相关的急性胰腺炎的其他病因（PSC、胰腺分裂症、药物性胰腺炎）。
