1. Departments of Radiation Oncology, Radiology and Urology, UT Health Science Center San Antonio, San Antonio, TX 78229, USA.
J Cancer. 2010 Dec 7;2:1-19.
Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even a survival advantage. In spite of those positive findings, there has been some reluctance to uniformly offer adjuvant treatment to patients. The perception is that the risk is not really high enough to warrant the risk of toxicity that comes with treatment. There are clearly factors that can help predict who is at the highest risk. Our purpose is to review those factors and identify patients that have a high enough risk justifying immediate treatment.
几项针对前列腺癌的随机研究表明,前列腺切除术患者术后立即进行治疗有获益。其中一项研究甚至显示出生存优势。尽管有这些积极的发现,但人们还是不愿意为所有患者提供辅助治疗。人们认为风险还不够高,无法承受治疗带来的毒性风险。显然,有一些因素可以帮助预测哪些患者的风险最高。我们的目的是回顾这些因素,并确定那些风险足够高的患者需要立即进行治疗。