Department of Oral Diagnosis and Surgery, Araraquara Dental School, UNESP- Sao Paulo State University, Araraquara, Sao Paulo, Brazil.
Int J Oral Maxillofac Implants. 2010 Nov-Dec;25(6):1125-30.
This study evaluated the effect of severe magnesium (Mg) dietary deficiency on systemic bone density and biomechanical resistance of bone tissue to the removal torque of osseointegrated implants.
The sample consisted of 45 rats; each received a titanium implant in their tibial metaphysis. After 60 days, the animals were divided into three groups (n = 15) according to their dietary Mg: the control group received the recommended content of Mg, group Mg1 received a 75% reduction in dietary Mg content, and group Mg2 was fed a diet with a 90% reduction in Mg content. Animals were sacrificed 150 days after implant placement. Serum concentrations of Mg were measured and the effect of Mg deficiency on systemic bone density was evaluated by densitometry of the lumbar vertebrae and femur. Biomechanical characteristics were measured by resistance of the bone tissue to removal of the implants.
Lower Mg serum concentrations were found for the Mg1 and Mg2 groups; however, densitometric analysis and torque evaluations showed a statistically significant difference only in the Mg2 group (P < .05). There was a statistically significant difference in removal torque between the Mg2 group and the control group.
This study showed that a severe deficiency of Mg decreased the systemic bone density and removal torque of osseointegrated implants.
本研究评估了严重镁（Mg）饮食缺乏对全身骨密度和骨组织对骨整合种植体去除扭矩的生物力学阻力的影响。
样本由 45 只大鼠组成；每只大鼠的胫骨干骺端均植入钛种植体。60 天后，根据饮食中的 Mg 将动物分为三组（n = 15）：对照组接受推荐量的 Mg，Mg1 组摄入的 Mg 量减少 75%，Mg2 组摄入的 Mg 量减少 90%。种植体植入 150 天后处死动物。测量血清中 Mg 的浓度，并通过腰椎和股骨的密度测定评估 Mg 缺乏对全身骨密度的影响。通过测量骨组织对种植体去除的阻力来评估生物力学特性。
Mg1 组和 Mg2 组的血清 Mg 浓度较低；然而，仅在 Mg2 组的密度分析和扭矩评估中发现具有统计学意义的差异（P <.05）。Mg2 组与对照组之间的去除扭矩有统计学差异。
本研究表明，严重的 Mg 缺乏会降低全身骨密度和骨整合种植体的去除扭矩。
