用于临床应用的脂肪来源干细胞：综述。
Adipose-derived stem cells for clinical applications: a review.
机构信息
Centre for Nanotechnology and Regenerative Medicine, Division of Surgery and Interventional Science, University College London, London, UK.
出版信息
Cell Prolif. 2011 Feb;44(1):86-98. doi: 10.1111/j.1365-2184.2010.00736.x.
Abstract
The use of stem cells derived from adipose tissue as an autologous and self-replenishing source for a variety of differentiated cell phenotypes, provides a great deal of promise for reconstructive surgery. In this article, we review available literature encompassing methods of extraction of pluripotent adipose stem cells (ASCs) from lipoaspirate locations, their storage, options for culture, growth and differentiation, cryopreservation and its effect on stem cell survival and proliferation, and new technologies involving biomaterials and scaffolds. We will conclude by assessing potential avenues for developing this incredibly promising field.
摘要
脂肪组织来源的干细胞作为自体和自我更新的多种分化细胞表型的来源，为重建外科提供了很大的希望。本文综述了从脂肪抽吸部位提取多能脂肪干细胞（ASCs）的方法、它们的储存、培养、生长和分化的选择、冷冻保存及其对干细胞存活和增殖的影响，以及涉及生物材料和支架的新技术。最后，我们将评估这个极具前景的领域的发展潜力。
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