Department of Psychology, Ealing NHS Trust, London, UK.
J Intellect Disabil Res. 2011 Feb;55(2):138-51. doi: 10.1111/j.1365-2788.2010.01371.x. Epub 2011 Jan 4.
The prevalence, phenomenology aetiology and correlates of four forms of challenging behaviour in 32 children and adults with Smith-Magenis syndrome (SMS) were investigated.
Cognitive assessments, questionnaires and semi-structured interviews were used to gather data on intellectual disability, verbal and physical aggression, destructive behaviour and self-injury and on characteristics known to be associated with aggression.
Aggression in SMS was more prevalent (87%), but not more severe than aggression in contrast groups. Aggressive behaviour was more frequently associated with environmental contingencies (e.g. attention, escape and access to tangibles) than self-injury and destructive behaviours. Severity of challenging behaviours was associated with high impulsivity.
Aggression is seen in the majority of people with SMS. Results suggest that behavioural disinhibition and operant social reinforcement are associated with the manifestation of aggression.
本研究调查了 32 名患有 Smith-Magenis 综合征（SMS）的儿童和成人的四种挑战性行为（包括攻击行为、破坏行为、自伤行为和冲动行为）的流行率、表现、病因学和相关因素。
采用认知评估、问卷调查和半结构化访谈等方法，收集智力障碍、言语和身体攻击、破坏行为和自伤行为以及与攻击行为相关的特征等方面的数据。
SMS 患者的攻击行为更为普遍（87%），但严重程度并不高于对照组。与自伤和破坏行为相比，攻击行为更常与环境条件（如注意力、逃避和获取实物）有关。挑战性行为的严重程度与高冲动性有关。
大多数 SMS 患者都存在攻击行为。结果表明，行为抑制障碍和操作性社会强化与攻击行为的表现有关。
