Jabbari Ali, Gonzalez Mercedes E, Franks Andrew G, Sanchez Miguel
Department of Dermatology, New York University, New York, NY, USA.
Dermatol Online J. 2010 Nov 15;16(11):23.
Laugier Hunziker syndrome is a rare disorder that is characterized by adult-onset hyperpigmented macules of the lips, oral cavity, and fingertips. Longitudinal melanonychia is present in the majority of cases. We present a 45-year-old woman with adult-onset hyperpigmented macules of the oral cavity as well as linear melanonychia that involved multiple fingernails. The history, clinical examination, and paucity of laboratory abnormalities or systemic findings support a diagnosis of Laugier Hunziker syndrome.
劳吉尔-杭齐克尔综合征是一种罕见的疾病,其特征为成人期出现的唇部、口腔和指尖色素沉着斑。大多数病例存在纵向黑甲。我们报告一例45岁女性,有成人期出现的口腔色素沉着斑以及累及多个指甲的线状黑甲。病史、临床检查以及实验室异常或全身表现较少支持劳吉尔-杭齐克尔综合征的诊断。