Department of Oral Medicine, Institute and Hospital of Stomatology, Nanjing University Medical School, Nanjing, China.
Int J Oral Sci. 2012 Dec;4(4):226-30. doi: 10.1038/ijos.2012.60. Epub 2012 Nov 23.
Laugier-Hunziker syndrome (LHS) is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. There is neither malignant predisposition nor underlying systemic abnormality associated with LHS. Herein, we present three uncommon cases of LHS with possibly new feature of nail pigmentation, which were diagnosed during the past 2 years. We also review the clinical and histological findings, differential diagnosis, and treatment of the syndrome in published literature.
劳吉尔-亨齐克综合征(LHS)是一种获得性色素沉着病,影响嘴唇、口腔黏膜和肢端区域,常伴有纵向黑甲。LHS 既没有恶性倾向,也没有与之相关的系统性异常。在此,我们报告了过去 2 年中诊断出的 3 例罕见的 LHS 病例,可能具有新的甲色素沉着特征。我们还回顾了文献中报道的该综合征的临床和组织学表现、鉴别诊断和治疗。