Studies on WE-3681, a novel aldose reductase inhibitor. III. Effects of WF-3681 and its derivatives on sorbitol accumulation in diabetic rats.
作者信息
Nishikawa M, Yoshida K, Okamoto M, Kohsaka M
机构信息
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
出版信息
J Antibiot (Tokyo). 1990 Sep;43(9):1186-8. doi: 10.7164/antibiotics.43.1186.
PMID:2120169
Abstract
摘要
相似文献
1
Studies on WE-3681, a novel aldose reductase inhibitor. III. Effects of WF-3681 and its derivatives on sorbitol accumulation in diabetic rats.新型醛糖还原酶抑制剂WE-3681的研究。III. WF-3681及其衍生物对糖尿病大鼠山梨醇蓄积的影响。
J Antibiot (Tokyo). 1990 Sep;43(9):1186-8. doi: 10.7164/antibiotics.43.1186.
2
Studies on WF-3681, a novel aldose reductase inhibitor. IV. Effect of FR-62765, a derivative of WF-3681, on the diabetic neuropathy in rats.新型醛糖还原酶抑制剂WF-3681的研究。IV. WF-3681的衍生物FR-62765对大鼠糖尿病性神经病变的影响。
J Antibiot (Tokyo). 1991 Apr;44(4):441-4. doi: 10.7164/antibiotics.44.441.
3
Potential aldose reductase inhibitors: 1,2,4-triazolidine-3,5-diones and 2-(3,4,5-trimethoxybenzoyl)-4,4-diethyl-3,5-isoxazolidinedione .潜在的醛糖还原酶抑制剂：1,2,4-三唑烷-3,5-二酮和2-(3,4,5-三甲氧基苯甲酰基)-4,4-二乙基-3,5-异恶唑烷二酮
Experientia. 1992 Apr 15;48(4):383-6. doi: 10.1007/BF01923435.
4
The effects of an aldose reductase inhibitor upon the sorbitol pathway, fructose-1-phosphate and lactate in the retina and nerve of streptozotocin-diabetic rats.醛糖还原酶抑制剂对链脲佐菌素诱导的糖尿病大鼠视网膜和神经中多元醇途径、1-磷酸果糖及乳酸的影响
Exp Eye Res. 1983 May;36(5):751-60. doi: 10.1016/0014-4835(83)90112-4.
5
The effects of aldose reductase inhibition on nerve sorbitol and myoinositol concentrations in diabetic and galactosemic rats.醛糖还原酶抑制对糖尿病和半乳糖血症大鼠神经山梨醇及肌醇浓度的影响。
Metabolism. 1984 Dec;33(12):1119-22. doi: 10.1016/0026-0495(84)90097-0.
6
The role of cyclic adenosine 3',5'-monophosphate and polyol metabolism in diabetic neuropathy.环磷腺苷和多元醇代谢在糖尿病性神经病变中的作用
J Clin Endocrinol Metab. 1992 Feb;74(2):393-8. doi: 10.1210/jcem.74.2.1370506.
7
Inhibition of polyol pathway activity in diabetic and galactosemic rats by the aldose reductase inhibitor CP-45,634.醛糖还原酶抑制剂CP - 45,634对糖尿病和半乳糖血症大鼠多元醇途径活性的抑制作用。
Adv Exp Med Biol. 1979;119:347-56. doi: 10.1007/978-1-4615-9110-8_51.
8
Sorbitol metabolism in the retina, optic nerve, and sural nerve of diabetic rats treated with an aldose reductase inhibitor.用醛糖还原酶抑制剂治疗的糖尿病大鼠视网膜、视神经和腓肠神经中的山梨醇代谢
Metabolism. 1988 Dec;37(12):1143-5. doi: 10.1016/0026-0495(88)90191-6.
9
Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol.山梨醇蓄积和肌醇耗竭在胰岛素缺乏的自发性糖尿病生物繁殖大鼠有髓大神经纤维结旁肿胀中的作用。胰岛素替代、醛糖还原酶抑制剂和肌醇的逆转作用。
J Clin Invest. 1987 May;79(5):1479-85. doi: 10.1172/JCI112977.
10
Increased nerve polyol levels in experimental diabetes and their reversal by Sorbinil.实验性糖尿病中神经多元醇水平升高及索比尼尔对其的逆转作用。
Br J Exp Pathol. 1988 Oct;69(5):697-702.
引用本文的文献
1
Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates.用于通过丙酮酸直接羟醛缩合反应对映选择性流动合成季碳异特窗酸的有机催化填充床反应器
Molecules. 2025 Jan 13;30(2):296. doi: 10.3390/molecules30020296.
Zotero 插件