• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

N-乙酰基-2-羟基-N'-[甲氧基(1-甲基吲哚-2-基)甲基]苯甲酰肼

N-Acetyl-2-hydroxy-N'-[methoxy(1-methylindol-2-yl)methyl]benzohydrazide.

作者信息

Yehye Wagee A, Rahman Noorsaadah Abdul, Ariffin Azhar, Ng Seik Weng

机构信息

Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 23;64(Pt 9):o1824. doi: 10.1107/S1600536808026846.

DOI:10.1107/S1600536808026846
PMID:21201799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2960481/
Abstract

In the crystal structure of the title Schiff-base, C(20)H(21)N(3)O(4), the amino group forms an N-H⋯O hydrogen bond to the acetyl group of an adjacent mol-ecule, forming a zigzag chain. The 2-hydr-oxy group is inter-nally hydrogen bonded to the amido group though an O-H⋯O hydrogen bond.

摘要

在标题席夫碱C(20)H(21)N(3)O(4)的晶体结构中，氨基与相邻分子的乙酰基形成N-H⋯O氢键，形成之字形链。2-羟基通过O-H⋯O氢键与酰胺基形成分子内氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200d/2960481/fecfbed2d1d1/e-64-o1824-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200d/2960481/fecfbed2d1d1/e-64-o1824-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200d/2960481/fecfbed2d1d1/e-64-o1824-fig1.jpg

相似文献

1
N-Acetyl-2-hydroxy-N'-[methoxy(1-methylindol-2-yl)methyl]benzohydrazide.N-乙酰基-2-羟基-N'-[甲氧基(1-甲基吲哚-2-基)甲基]苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 23;64(Pt 9):o1824. doi: 10.1107/S1600536808026846.
2
2-Hydr-oxy-N'-(2-methoxy-naphthyl-idene)benzohydrazide.2-羟基-N'-(2-甲氧基萘基亚甲基)苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 23;64(Pt 9):o1829-30. doi: 10.1107/S1600536808026962.
3
2-Hydr-oxy-N'-(2-hydr-oxy-4-methoxy-benzyl-idene)-3-methyl-benzohydrazide monohydrate.2-羟基-N'-(2-羟基-4-甲氧基亚苄基)-3-甲基苯甲酰肼一水合物
Acta Crystallogr Sect E Struct Rep Online. 2010 May 15;66(Pt 6):o1340. doi: 10.1107/S1600536810016855.
4
The cocrystal 2-hydr-oxy-4-methyl-N-propanoylbenzohydrazide-2-hydr-oxy-N-(2-hydr-oxy-4-methyl-benzo-yl)-6-methyl-benzohydrazide (2/1).共晶体2-羟基-4-甲基-N-丙酰基苯甲酰肼-2-羟基-N-(2-羟基-4-甲基苯甲酰基)-6-甲基苯甲酰肼(2/1)
Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 18;64(Pt 11):o2144. doi: 10.1107/S1600536808033515.
5
N'-[(2-Hydr-oxy-1-naphth-yl)methyl-idene]-2-nitro-benzohydrazide.N'-[(2-羟基-1-萘基)亚甲基]-2-硝基苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2010 Apr 28;66(Pt 5):o1177. doi: 10.1107/S160053681001490X.
6
N'-(2-Hydr-oxy-4-methoxy-benzyl-idene)-4-methoxy-benzohydrazide.N'-(2-羟基-4-甲氧基-亚苄基)-4-甲氧基-苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 22;65(Pt 9):o2200. doi: 10.1107/S1600536809032449.
7
N'-(5-Bromo-2-hydr-oxy-3-methoxy-benzyl-idene)-4-hydr-oxy-3-methoxy-benzohydrazide dihydrate.N'-(5-溴-2-羟基-3-甲氧基亚苄基)-4-羟基-3-甲氧基苯甲酰肼二水合物
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 29;65(Pt 9):o2259. doi: 10.1107/S1600536809033522.
8
(E)-N'-(4-Hydroxy-benzyl-idene)-2-methoxy-benzohydrazide.（E）-N'-（4-羟基-亚苄基）-2-甲氧基-苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 24;64(Pt 10):o1999. doi: 10.1107/S1600536808029334.
9
N'-(4-Hydr-oxy-3-methoxy-benzyl-idene)acetohydrazide monohydrate.N'-(4-羟基-3-甲氧基-亚苄基)乙酰肼一水合物
Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65(Pt 10):o2514. doi: 10.1107/S1600536809037489.
10
(E)-4-Bromo-N'-(2-hydr-oxy-1-naphthyl-methyl-ene)benzohydrazide.（E）-4-溴-N'-（2-羟基-1-萘基亚甲基）苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 4;64(Pt 11):o2070. doi: 10.1107/S1600536808031395.

引用本文的文献

1
N'-(3-Bromo-5-chloro-2-hy-droxy-benzyl-idene)-2H-1,3-benzodioxole-5-carbo-hydrazide.N'-(3-溴-5-氯-2-羟基苄叉基)-2H-1,3-苯并二恶唑-5-碳酰肼
Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1336-7. doi: 10.1107/S160053681201433X. Epub 2012 Apr 6.
2
(E)-N'-(5-Bromo-2-meth-oxy-benzyl-idene)isonicotinohydrazide.（E）-N'-（5-溴-2-甲氧基-亚苄基）异烟肼
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1443. doi: 10.1107/S1600536811017910. Epub 2011 May 20.
3
(E)-4-Meth-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide methanol monosolvate.

本文引用的文献

1
Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents.新型4-吡咯-1-基苯甲酰肼类似物以及一些衍生的恶二唑、三唑和吡咯环系统的合成：一类新型潜在抗菌和抗结核药物。
Eur J Med Chem. 2008 Sep;43(9):1989-96. doi: 10.1016/j.ejmech.2007.11.016. Epub 2007 Dec 5.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
3
Synthesis, structure, and bioactivity of N'-substituted benzylidene-3,4,5-trimethoxybenzohydrazide and 3-acetyl-2-substituted phenyl-5-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1,3,4-oxadiazole derivatives.
（E）-4-甲氧基-N'-（4-硝基亚苄基）苯甲酰肼甲醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3240. doi: 10.1107/S160053681004701X.
4
(E)-4-Hydr-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide.（E）-4-羟基-N'-（4-硝基亚苄基）苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 6;65(Pt 7):o1466. doi: 10.1107/S1600536809020066.
5
(E)-N'-(4-Hydroxy-benzyl-idene)-4-hydroxy-benzohydrazide methanol solvate.（E）-N'-（4-羟基-亚苄基）-4-羟基-苯甲酰肼甲醇溶剂化物
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 6;65(Pt 7):o1465. doi: 10.1107/S1600536809020078.
6
(E)-N'-(5-Bromo-2-methoxy-benzyl-idene)-3-methoxy-benzohydrazide.（E）-N'-（5-溴-2-甲氧基-亚苄基）-3-甲氧基-苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 28;65(Pt 4):o883. doi: 10.1107/S1600536809010435.
7
(E)-N'-[1-(2-Hydroxy-phen-yl)ethyl-idene]-3-methoxy-benzohydrazide.（E）-N'-[1-（2-羟基苯基）亚乙基]-3-甲氧基苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 28;65(Pt 4):o876. doi: 10.1107/S1600536809010228.
8
(E)-N'-(5-Bromo-2-methoxy-benzyl-idene)-4-methoxy-benzohydrazide.（E）-N'-（5-溴-2-甲氧基-亚苄基）-4-甲氧基-苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 8;64(Pt 12):o2260. doi: 10.1107/S1600536808035472.
9
(E)-N'-(2-Chloro-5-nitro-benzyl-idene)-4-methoxy-benzohydrazide.（E）-N'-（2-氯-5-硝基-亚苄基）-4-甲氧基-苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 25;64(Pt 11):o2177. doi: 10.1107/S1600536808034107.
10
(E)-2-Meth-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide.（E）-2-甲氧基-N'-（4-硝基亚苄基）苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 28;65(Pt 12):o3272. doi: 10.1107/S160053680905079X.
N'-取代亚苄基-3,4,5-三甲氧基苯甲酰肼及3-乙酰基-2-取代苯基-5-(3,4,5-三甲氧基苯基)-2,3-二氢-1,3,4-恶二唑衍生物的合成、结构与生物活性
Bioorg Med Chem Lett. 2006 Oct 1;16(19):5036-40. doi: 10.1016/j.bmcl.2006.07.048. Epub 2006 Jul 28.
4
New antimitotic agents with activity in multi-drug-resistant cell lines and in vivo efficacy in murine tumor models.在多药耐药细胞系中具有活性且在小鼠肿瘤模型中具有体内疗效的新型抗有丝分裂剂。
J Med Chem. 2001 Dec 6;44(25):4416-30. doi: 10.1021/jm010231w.