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（4S）-4-（3,4-二氯苯基）-1'-甲基-4'-苯基-3,4-二氢萘-2-螺-3'-吡咯烷-2'-螺-1''-苊烯-1,2''（2H，1''H）-二酮

(4S)-4-(3,4-Dichloro-phen-yl)-1'-methyl-4'-phenyl-3,4-dihydronaphthalene-2-spiro-3'-pyrrolidine-2'-spiro-1''-acenaphthyl-ene-1,2''(2H,1''H)-dione.

作者信息

Murugan R, Gunasekaran B, Narayanan S Sriman, Manivannan V

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 May 17;64(Pt 6):o1089. doi: 10.1107/S1600536808013846.

DOI:10.1107/S1600536808013846
PMID:21202604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2961525/
Abstract

In the title compound, C(37)H(27)Cl(2)NO(2), the 3,4-dichloro-phenyl ring makes a dihedral angle of 46.66 (6)° with the phenyl ring. The mol-ecular structure is stabilized by weak intra-molecular C-H⋯O inter-actions and the crystal structure is stabilized by weak inter-molecular C-H⋯O inter-actions. The C-C-C-C-C five-membered ring is planar, while the C-C-C-C-N five-membered ring adopts a half-chair conformation.

摘要

在标题化合物C(37)H(27)Cl(2)NO(2)中，3,4-二氯苯基环与苯基环形成的二面角为46.66 (6)°。分子结构通过弱分子内C-H⋯O相互作用得以稳定，晶体结构则通过弱分子间C-H⋯O相互作用得以稳定。C-C-C-C-C五元环是平面的，而C-C-C-C-N五元环呈半椅式构象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6221/2961525/6b963ceb794e/e-64-o1089-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6221/2961525/15874c68fd09/e-64-o1089-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6221/2961525/6b963ceb794e/e-64-o1089-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6221/2961525/15874c68fd09/e-64-o1089-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6221/2961525/6b963ceb794e/e-64-o1089-fig2.jpg

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本文引用的文献

1
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.
J Med Chem. 1984 Nov;27(11):1508-15. doi: 10.1021/jm00377a021.