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[2009年甲型H1N1流感大流行在一所军事学院的爆发:西班牙社区传播的开始]

[Pandemic influenza (H1N1) 2009 Outbreak in a Military Academy: start of community circulation in Spain].

作者信息

Mayo Montero Elga, Ballester Orcal Elena, Piñeyroa Sierra Antonio Joaquín, Fé Marques Antonio, Santa-Olalla Peralta Patricia, Sierra Moros Maria José

机构信息

Instituto de Medicina Preventiva de la Defensa Capitán Médico Ramón y Cajal (IMPDEF), Ministerio de Defensa de España, Madrid, Spain.

出版信息

Rev Esp Salud Publica. 2010 Sep-Oct;84(5):597-607. doi: 10.1590/s1135-57272010000500011.

DOI:10.1590/s1135-57272010000500011
PMID:21203722
Abstract

BACKGROUND

On May 19, 2009, 21 cases of influenza-like illness were reported among soldiers from an Engineering Military Academy (ACING) in Hoyo de Manzanares, Spain. In the context of an influenza A (H1N1)2009 global alert, it was decided to investigate a possible pandemic influenza outbreak. To describe a possible outbreak of influenza A (H1N1)2009 in a Military Training Centre and to describe the measures adopted for transmission control of this new infection.

METHODS

A specific questionnaire was administered and biological samples were collected from all cases under investigation. Isolation and quarantine were recommended for cases and contacts, respectively.

RESULTS

Eighty-one cases were confirmed. Among 52 samples tested, 31 were positive for influenza virus A/California/7/2009. The average age of the cases was 22.0 years (range 18-31 years) and 84% were men. Most common reported symptoms were cough and fever. All cases were isolated and treated with oseltamivir, with full recovery. The total attack rate was 12.42%. None of the cases had history of travel to risk areas or contact with previously diagnosed cases outside the academy. Thirty-one confirmed cases related to this outbreak were identified outside the academy, 24 cases were family contacts and friends.

CONCLUSIONS

This outbreak was the first evidence of community transmission of pandemic influenza H1N1 in Spain. The rapid detection of this outbreak enhanced an early implementation of measures aiming at the containment of its transmission.

摘要

背景

2009年5月19日,西班牙曼萨纳雷斯镇奥约的一所工程军事学院(ACING)的士兵中报告了21例流感样疾病病例。在甲型H1N1流感2009年全球警报的背景下,决定对可能的甲型H1N1流感大流行疫情进行调查。描述军事训练中心可能发生的甲型H1N1流感2009年疫情,并描述为控制这种新感染的传播所采取的措施。

方法

发放了一份特定问卷,并从所有受调查病例中采集了生物样本。建议分别对病例和接触者进行隔离和检疫。

结果

确诊81例。在检测的52份样本中,31份甲型流感病毒A/加利福尼亚/7/2009呈阳性。病例的平均年龄为22.0岁(范围18 - 31岁),84%为男性。报告的最常见症状是咳嗽和发热。所有病例均被隔离并用奥司他韦治疗,全部康复。总发病率为12.42%。所有病例均无前往高危地区旅行史或在学院外与先前确诊病例接触史。在学院外确认了31例与此次疫情相关的病例,其中24例是家庭接触者和朋友。

结论

此次疫情是西班牙甲型H1N1流感大流行社区传播的首个证据。此次疫情的快速发现促使早期实施旨在控制其传播的措施。

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