水通道蛋白4抗体阳性视神经脊髓炎合并抗利尿激素分泌异常综合征

Aquaporin-4 antibody positive neuromyelitis optica with syndrome of inappropriate antidiuretic hormone secretion.

作者信息

You Xiao-Fan, Qin Wei, Hu Wen-Li

机构信息

Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing 100020, China.

出版信息

Neurosciences (Riyadh). 2011 Jan;16(1):68-71.

PMID:21206449

Abstract

Neuromyelitis optica (NMO) has been reported to be associated with endocrinopathies, such as amenorrhea, galactorrhea, and diabetes mellitus. However, its association with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is extremely rare. We herein report an adult case of NMO with SIADH in a female Chinese patient. The patient was aquaporin-4 antibody positive, and her hypothalamic dysfunction may have been related to the development of SIADH.

摘要

视神经脊髓炎（NMO）已被报道与内分泌病相关，如闭经、溢乳和糖尿病。然而，其与抗利尿激素分泌不当综合征（SIADH）的关联极为罕见。我们在此报告一名成年中国女性NMO合并SIADH的病例。该患者水通道蛋白4抗体呈阳性，其下丘脑功能障碍可能与SIADH的发生有关。