对用双硫仑治疗酗酒患者进行肺量测定和气道反应性研究。
Study of spirometry and airway reactivity in patients on disulfirm for treatment of alcoholism.
机构信息
R.B. GALGALI, M.D.,D.P.M., D.N.B., Associate Professor, Department of Psychiatry, St. John's Medical College Hospital, Sarjapur Road, Bangalore-560034.
出版信息
Indian J Psychiatry. 2002 Jul;44(3):273-6.
Abstract
The aim of our study was to examine the short term effect ofdisulfiram on pulmonary functions of alcohol dependent subjects, who were chronic smokers J/Ve compared FEV1 % values on spirometry and airway reactivity to histamine challenge in alcohol dependent subjects at baseline and after 2 weeks of treatment with disulfiram. Disulfiram did not significantly alter FEVI values and airway reactivity during the treatment period and can thus be used safely in alcohol dependent subjects who are current smokers.
摘要
我们的研究目的是观察双硫仑对慢性吸烟的酒精依赖患者肺功能的短期影响，通过比较基线时和接受双硫仑治疗 2 周后支气管激发试验中 FEV1%值，评估酒精依赖患者的气道反应性。在治疗期间，双硫仑并未显著改变 FEV1 值和气道反应性，因此，双硫仑可安全用于目前吸烟的酒精依赖患者。
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