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[从跨学科指南角度看隐睾症与不育症]

[Cryptorchidism and infertility from the perspective of interdisciplinary guidelines].

作者信息

Mathers M J, Degener S, Roth S

机构信息

Urologische Gemeinschaftspraxis Remscheid, Kooperationspraxis der Klinik für Urologie und Kinderurologie, Helios Klinikum Wuppertal, Universität Witten/Herdecke, Fastenrathstraße 1, 42853 Remscheid, Deutschland.

出版信息

Urologe A. 2011 Jan;50(1):20-5. doi: 10.1007/s00120-010-2438-x.

DOI:10.1007/s00120-010-2438-x
PMID:21207009
Abstract

Cryptorchidism is the most common genital disorder in boys. Early-born boys are affected in up to one third of the cases, while about 2-5% of full-term newborns suffer from at least one undescended testicle. As a result of short-term endogenous testosterone secretion after birth the prevalence decreases to 1-2% after 3 months. According to most studies, watchful waiting after 6 months is not justified because after this time spontaneous testicular descent only very rarely occurs. Even though the effects of testicular development and fertility in undescended testis have been extensively examined, the only fact that remains certain is that approximately 90% of untreated men with bilateral cryptorchidism develop azoospermia. The remaining scenarios of cryptorchidism (unilateral, ectopic, inguinal, treated or not treated) exhibit unpredictable fertility and likelihood of fatherhood.

摘要

隐睾症是男孩中最常见的生殖系统疾病。早产男孩中高达三分之一会受其影响,而约2 - 5%的足月儿至少有一侧睾丸未降。由于出生后短期内内源性睾酮分泌,3个月后患病率降至1 - 2%。根据大多数研究,6个月后进行观察等待并不合理,因为在此之后睾丸很少会自然下降。尽管对未降睾丸的睾丸发育和生育能力的影响已进行了广泛研究,但唯一确定的事实是,约90%未经治疗的双侧隐睾症男性会出现无精子症。隐睾症的其他情况(单侧、异位、腹股沟型、已治疗或未治疗)生育能力和生育可能性难以预测。

相似文献

1
[Cryptorchidism and infertility from the perspective of interdisciplinary guidelines].[从跨学科指南角度看隐睾症与不育症]
Urologe A. 2011 Jan;50(1):20-5. doi: 10.1007/s00120-010-2438-x.
2
[Quality assurance in andrological surgery].男科手术中的质量保证
Urologe A. 2011 Jan;50(1):17-9. doi: 10.1007/s00120-010-2441-2.
3
The undescended testis: diagnosis, treatment and long-term consequences.隐睾:诊断、治疗及长期后果
Dtsch Arztebl Int. 2009 Aug;106(33):527-32. doi: 10.3238/arztebl.2009.0527. Epub 2009 Aug 14.
4
The relationship of cryptorchidism to fertility.隐睾症与生育能力的关系。
Curr Urol Rep. 2004 Apr;5(2):142-8. doi: 10.1007/s11934-004-0028-4.
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Cryptorchidism隐睾症
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Opinion: Comment on Evaluation and Treatment of Cryptorchidism: AUA/AAP and Nordic Consensus Guidelines.观点:关于隐睾症评估与治疗的评论:美国泌尿外科学会/美国儿科学会及北欧共识指南
Urol Int. 2016;96(3):249-54. doi: 10.1159/000443741. Epub 2016 Jan 30.
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Testicular descent: when to interfere?睾丸下降:何时进行干预?
Eur J Pediatr Surg. 2001 Jun;11(3):173-6. doi: 10.1055/s-2001-15484.
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Testicular histology related to fertility outcome and postpubertal hormone status in cryptorchidism.隐睾症中与生育结局及青春期后激素状态相关的睾丸组织学
Klin Padiatr. 2008 Sep-Oct;220(5):302-7. doi: 10.1055/s-2007-993194. Epub 2008 Apr 9.
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Management of undescended testis.隐睾的管理
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10
No relationship of testicular size at orchiopexy with fertility in men who previously had unilateral cryptorchidism.对于既往有单侧隐睾症的男性,睾丸固定术中睾丸大小与生育能力之间无相关性。
J Urol. 2001 Jul;166(1):236-9.

引用本文的文献

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[Prevalence of male infertility in a university hospital in Morocco].[摩洛哥一家大学医院男性不育症的患病率]
Pan Afr Med J. 2021 Jan 15;38:46. doi: 10.11604/pamj.2021.38.46.19633. eCollection 2021.

本文引用的文献

1
The undescended testis: diagnosis, treatment and long-term consequences.隐睾:诊断、治疗及长期后果
Dtsch Arztebl Int. 2009 Aug;106(33):527-32. doi: 10.3238/arztebl.2009.0527. Epub 2009 Aug 14.
2
Testicular histology related to fertility outcome and postpubertal hormone status in cryptorchidism.隐睾症中与生育结局及青春期后激素状态相关的睾丸组织学
Klin Padiatr. 2008 Sep-Oct;220(5):302-7. doi: 10.1055/s-2007-993194. Epub 2008 Apr 9.
3
Infertility in cryptorchidism is linked to the stage of germ cell development at orchidopexy.
隐睾症中的不育与睾丸固定术时生殖细胞发育阶段有关。
Horm Res. 2007;68(1):46-52. doi: 10.1159/000100874. Epub 2007 Mar 14.
4
Nordic consensus on treatment of undescended testes.关于隐睾治疗的北欧共识。
Acta Paediatr. 2007 May;96(5):638-43. doi: 10.1111/j.1651-2227.2006.00159.x. Epub 2007 Feb 26.
5
[Multimodal therapy of cryptorchism].[隐睾症的多模式治疗]
Urologe A. 2006 Sep;45 Suppl 4:214-8. doi: 10.1007/s00120-006-1185-5.
6
Germ cell development in the descended and cryptorchid testis and the effects of hormonal manipulation.下降型睾丸和隐睾中生殖细胞的发育以及激素调控的影响。
Pediatr Surg Int. 2005 Apr;21(4):240-54. doi: 10.1007/s00383-005-1382-0. Epub 2005 Feb 23.
7
Neoadjuvant gonadotropin-releasing hormone therapy before surgery may improve the fertility index in undescended testes: a prospective randomized trial.术前新辅助促性腺激素释放激素治疗可能改善隐睾的生育指数:一项前瞻性随机试验。
J Urol. 2005 Mar;173(3):974-7. doi: 10.1097/01.ju.0000153562.07287.77.
8
The role of testicular vascular anatomy in the salvage of high undescended testes.睾丸血管解剖结构在高位隐睾挽救中的作用。
Aust N Z J Surg. 1959 Aug;29:92-106. doi: 10.1111/j.1445-2197.1959.tb03826.x.
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Groin exploration for nonpalpable testes: laparoscopic approach.
J Pediatr Surg. 2002 Nov;37(11):1552-5. doi: 10.1053/jpsu.2002.36183.
10
Cryptorchidism, its impact on male fertility.
Eur Urol. 2002 Feb;41(2):121-3. doi: 10.1016/s0302-2838(01)00040-9.