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[摩洛哥一家大学医院男性不育症的患病率]

[Prevalence of male infertility in a university hospital in Morocco].

作者信息

Frikh Mohammed, Benaissa Mostafa, Kasouati Jalal, Benlahlou Yassine, Chokairi Omar, Barkiyou Malika, Chadli Meryama, Maleb Adil, Elouennass Mostafa

机构信息

Service de Bactériologie, Université Mohammed V, Faculté de Médecine et Pharmacie, Hôpital Militaire d´Instruction Mohammed V, Rabat, Maroc.

Laboratoire d´Histo-embryologie et Cytogénétique, Faculté de Médecine et de Pharmacie, Université Mohamed V, Rabat, Maroc.

出版信息

Pan Afr Med J. 2021 Jan 15;38:46. doi: 10.11604/pamj.2021.38.46.19633. eCollection 2021.

Abstract

INTRODUCTION

infertility in couples has become a public health problem in recent years. It can be related to a problem in the male, female or both. Men infertility accounts for 40% of cases. In Morocco, most studies have focused on the causes and risk factors for male infertility. The purpose of our study was to assess the prevalence of male infertility and semen parameters in infertile men or in men at high risk of developing infertility in a tertiary hospital in Rabat.

METHODS

we conducted an analysis of 482 patients referred for evaluation of infertility in the couple or as part of preoperative assessment of varicocele or testicular ectopia. Demographic data, risk factors for infertility, primary or secondary infertility were recorded for each patient. Semen parameters were assessed and interpreted according to WHO standards updated in 2010 based on studies of factors associated with their disturbance.

RESULTS

the average age of patients was 35.35±8.81 years. Primary infertility was found in 61.8% of cases. The most common risk factors for infertility were tobacco followed by varicocele and infection. Spermogram was altered in 53.1% of cases. The most common abnormality was sperm vitality issues (36.9%) followed by spermatic concentration (29.7%) and morphology (29.3%). Age was the unique factor which had a significant impact on spermogram (p=0.002). Abnormalities in mobility were detected in patients ≥31 years, sperm vitality issues in patients aged 34 years, abnormalities in morphology in patients aged 35 years and concentration in patients aged 37 years. Azoospermia was found in 16.4% of cases and was mainly associated with primary infertility. Oligo-astheno-teratozoospermia was the most common association (26.2%).

CONCLUSION

male infertility is common in our context. The major risk factor is age. Mobility is the earliest parameter achieved.

摘要

引言

近年来,夫妻不育已成为一个公共卫生问题。它可能与男性、女性或双方的问题有关。男性不育占病例的40%。在摩洛哥,大多数研究都集中在男性不育的原因和风险因素上。我们研究的目的是评估拉巴特一家三级医院中不育男性或有高不育风险男性的男性不育患病率和精液参数。

方法

我们对482例因夫妻不育评估或作为精索静脉曲张或睾丸异位症术前评估一部分而转诊的患者进行了分析。记录了每位患者的人口统计学数据、不育风险因素、原发性或继发性不育情况。根据2010年更新的世界卫生组织标准,基于与其紊乱相关因素的研究,对精液参数进行评估和解释。

结果

患者的平均年龄为35.35±8.81岁。61.8%的病例为原发性不育。最常见的不育风险因素是吸烟,其次是精索静脉曲张和感染。53.1%的病例精液分析异常。最常见的异常是精子活力问题(36.9%),其次是精子浓度(29.7%)和形态(29.3%)。年龄是对精液分析有显著影响的唯一因素(p = 0.002)。≥31岁的患者检测到运动异常,34岁的患者有精子活力问题,35岁的患者有形态异常,37岁的患者有浓度异常。16.4%的病例发现无精子症,主要与原发性不育有关。少弱畸精子症是最常见的组合(26.2%)。

结论

在我们的研究背景下,男性不育很常见。主要风险因素是年龄。运动是最早出现异常的参数。

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