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袋狸(短尾矮袋鼠)胎儿和新生儿的免疫球蛋白G水平。

Immunoglobulin G levels in fetal and newborn tammar wallabies (Macropus eugenii).

作者信息

Deane E M, Cooper D W, Renfree M B

机构信息

School of Biological Sciences, Macquarie University, N.S.W., Australia.

出版信息

Reprod Fertil Dev. 1990;2(4):369-75. doi: 10.1071/rd9900369.

DOI:10.1071/rd9900369
PMID:2120744
Abstract

Immunoglobulin G (IgG) was measured in fetal, neonatal and colostral samples from the tammar wallaby (Macropus eugenii) in order to study the possibility of passively acquired immunity. Samples were obtained from young at a known stage of gestation and at known times (to the minute) after birth. IgG was present (in increasing levels of concentration) in fetal serum, neonatal serum and colostrum. Since the fetus and neonate are probably unable to make immunoglobulin (Ig), it is hypothesized that transplacental and trans-gut transmission takes place from mother to offspring. The vascular yolk sac placenta has a high concentration of IgG, and is the most likely route of transmission from mother to young. Some observations were made of IgA which was found only in colostrum. No Ig of either kind was found in yolk sac fluid.

摘要

为了研究被动获得性免疫的可能性,对帚尾袋貂(赤褐袋鼠)的胎儿、新生儿和初乳样本中的免疫球蛋白G(IgG)进行了测量。样本取自处于已知妊娠阶段以及出生后已知时间(精确到分钟)的幼崽。IgG存在于胎儿血清、新生儿血清和初乳中(浓度呈上升趋势)。由于胎儿和新生儿可能无法产生免疫球蛋白(Ig),因此推测存在从母体到后代的经胎盘和经肠道传播。血管卵黄囊胎盘含有高浓度的IgG,是母体向幼崽传播的最可能途径。对仅在初乳中发现的IgA进行了一些观察。在卵黄囊液中未发现任何一种Ig。

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Immunoglobulin G levels in fetal and newborn tammar wallabies (Macropus eugenii).袋狸(短尾矮袋鼠)胎儿和新生儿的免疫球蛋白G水平。
Reprod Fertil Dev. 1990;2(4):369-75. doi: 10.1071/rd9900369.
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