Pharm Biol. 2000;38(4):308-12. doi: 10.1076/1388-0209(200009)3841-AFT308.
In addition to bergapten ( 1 ), xanthotoxin ( 2 ), isopimpinellin ( 3 ), imperatorin ( 4 ), and pimpinellin ( 5 ), for the first time 5,7-disubstituted simple coumarins, limettin (5,7-dimethoxycoumarin) ( 6 ) and a new compound 5-methoxy-7-(3,3-dimethylalliloxy)-coumarin ( 7 ), have been isolated from the fruits of Heracleum mantegazzianum Somm. et Lev. The new compound 7 is a derivative of anisocoumarin B. The structures of 6 and 7 were determined on the basis of 1D and 2D NMR spectra.
除了佛手柑内酯（1）外，还首次从独活属植物果实中分离得到了花椒毒素（2）、异茴芹素（3）、花椒素（4）和茴芹素（5），5,7-二取代简单香豆素，柠檬素（5,7-二甲氧基香豆素）（6）和一种新化合物 5-甲氧基-7-（3,3-二甲基丙烯酰氧基）-香豆素（7）。新化合物 7 是anisocoumarin B 的衍生物。基于 1D 和 2D NMR 谱确定了 6 和 7 的结构。
