Chen Meng-shi, Yang Hua-lin, Chen Yan-fang, Tan Hong-zhuan, Bai Li-qiong, Zhang Yan-hui, Liu Jun, Li Gui-ping
Department of Epidemiology, School of Public Health, Central South University, Changsha 410078, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Feb;31(2):151-4.
To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the co-infection.
A 1:2 matched nested case-control study was carried out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.
1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person-years, among them 62 tuberculosis cases were diagnosed. The incidence density of tuberculosis among people living with HIV/AIDS was 8.42 persons per 100 person-years. Factors as education level(OR = 0.483), vaccination history of Bacille Calmette Guerin (OR = 0.561), CD(4)(+) count T-lymphocyte (OR = 0.356), unemployment (OR = 1.976), living alone (OR = 2.646), and smoking (OR = 2.215) were significantly related to the prevalence of tuberculosis among people living with HIV/AIDS.
High education level, with vaccination history of Bacille Calmette Guerin and high level of CD(4)(+) T-lymphocyte count were protective factors while being unemployed, living alone, and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HIV/AIDS.
确定与艾滋病毒/艾滋病感染者结核病感染相关的危险因素，并制定预防合并感染的策略。
开展一项1:2匹配的巢式病例对照研究，以分析艾滋病毒/艾滋病感染者中结核病的影响因素。
对1018名艾滋病毒/艾滋病感染者进行了为期一年的随访，累计人年数为736.75人年，其中确诊62例结核病病例。艾滋病毒/艾滋病感染者中结核病的发病密度为每100人年8.42人。教育水平（OR = 0.483）、卡介苗接种史（OR = 0.561）、CD4(+) T淋巴细胞计数（OR = 0.356）、失业（OR = 1.976）、独居（OR = 2.646）和吸烟（OR = 2.215）等因素与艾滋病毒/艾滋病感染者中结核病的患病率显著相关。
高教育水平、有卡介苗接种史和高水平的CD4(+) T淋巴细胞计数是保护因素，而失业、独居和吸烟习惯是与艾滋病毒/艾滋病感染者中结核病患病率相关的危险因素。
