Department of Urology, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA.
Urology. 2011 Jun;77(6):1288-91. doi: 10.1016/j.urology.2010.08.066. Epub 2011 Jan 7.
To complete a prospective evaluation of serum amylase and lipase levels before and after shock wave lithotripsy (SWL) for renal stones. We also compared these serum levels to those of patients undergoing percutaneous and ureteroscopic stone surgery. SWL injury to the pancreas should be noted by an increase in serum amylase and lipase.
A prospective evaluation of 38 patients (16 who underwent SWL, 15 who underwent percutaneous nephrostolithotomy, and 7 who underwent ureteroscopic stone manipulation) who underwent treatment of renal calculi at our institution was completed. The control group was the combined group of patients who had undergone percutaneous nephrostolithotomy or ureteroscopic stone manipulation. The serum amylase and lipase levels were measured before the procedure, immediately after the procedure (2 hours), and ≥30 days after the procedure.
No statistically significant difference was found in the change from before to immediately after the procedure between the SWL group and the controls in amylase (median decrease 6 U/L vs 11 U/L, P = .45) or lipase (median decrease 4 U/L vs 9 U/L, P = .31). Also, no statistically significant evidence was seen in the change from before to >30 days after the procedure between the SWL group and controls in the amylase level (median increase 0 U/L vs 2 U/L, P = 1.00) or lipase (median change 2 U/L increase vs 1 U/L decrease, P = .96).
SWL does not appear to noticeably increase the serum amylase and lipase level directly postoperatively or >30 days after the procedure compared with baseline or compared with the controls.
在冲击波碎石术（SWL）治疗肾结石前后，完成血清淀粉酶和脂肪酶水平的前瞻性评估。我们还将这些血清水平与接受经皮和输尿管镜取石术的患者进行比较。SWL 对胰腺的损伤应表现为血清淀粉酶和脂肪酶升高。
对在我院接受肾结石治疗的 38 名患者（16 名接受 SWL，15 名接受经皮肾镜碎石术，7 名接受输尿管镜取石术）进行了前瞻性评估。对照组为接受经皮肾镜碎石术或输尿管镜取石术的患者。在术前、术后即刻（2 小时）和术后≥30 天测量血清淀粉酶和脂肪酶水平。
SWL 组和对照组在淀粉酶（中位数降低 6 U/L 与 11 U/L，P =.45）或脂肪酶（中位数降低 4 U/L 与 9 U/L，P =.31）从术前到术后即刻的变化方面，差异无统计学意义。同样，SWL 组和对照组在淀粉酶水平（中位数升高 0 U/L 与 2 U/L，P = 1.00）或脂肪酶（中位数升高 2 U/L 与降低 1 U/L，P =.96）从术前到术后≥30 天的变化方面，也无统计学意义。
与基线或对照组相比，SWL 似乎不会明显增加术后即刻或术后>30 天的血清淀粉酶和脂肪酶水平。
