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[抗坏血酸对暴露于氯化钴的人体细胞的保护作用]

[Protective effect of ascorbic acid in cells of people exposed to cobalt chloride].

作者信息

L'vova G N, Chopikashvili L V, Vasil'eva I M, Zasukhina G D

出版信息

Genetika. 1990 Jul;26(7):1316-9.

PMID:2121602
Abstract

The workers contacting with cobalt chloride for 10 years and more have been receiving 50 mg ascorbic acid for 30 days. DNA repair was analysed after this procedure in lymphocytes cultivated in vitro according to following criteria: reactivation and induced mutagenesis of vaccinia virus as well as formation of DNA breaks and their resynthesis upon treatment with cobalt chloride and 4-nitro-quinoline-1-oxide.

摘要

接触氯化钴10年及以上的工人连续30天每天服用50毫克抗坏血酸。按照以下标准在体外培养的淋巴细胞中对该程序后的DNA修复进行分析:痘苗病毒的复活和诱导诱变以及在用氯化钴和4-硝基喹啉-1-氧化物处理时DNA断裂的形成及其再合成。

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