Gandhi Sumir, Lata Jeevan, Gandhi Nitasha
Department of Oral & Maxillofacial Surgery, Christian Dental College, Christian Medical College, Ludhiana, India.
J Oral Maxillofac Surg. 2011 Jun;69(6):1668-77. doi: 10.1016/j.joms.2010.06.188. Epub 2011 Jan 8.
Oral lesions usually lead to a diagnostic dilemma. Fine needle aspiration cytology (FNAC) is an important diagnostic aid for making a preoperative diagnosis of oral lesions. It does not supplant histopathology but augments it.
FNAC of oral lesions was undertaken in 45 patients, and all the lesions were subjected to histopathologic examination. Aspiration was performed with 23- to 25-gauge needles held in a Cameco syringe holder (Amar Udyog, Chandigarh, India).
We diagnosed benign lesions in 22 cases, malignant lesions in 15, and inflammatory lesions in 7 by FNAC, whereas in 1 case the specimen was insufficient for diagnosis. One result was false negative, but there was no false-positive result. Specificity and sensitivity of FNAC were 95.45% and 93.75%, respectively. FNAC gave a diagnostic accuracy of 90.0% for benign lesions, 94.0% for malignant lesions, and 100% for inflammatory lesions.
The procedure does not have any side effects or complications. Hence FNAC can be used as a reliable diagnostic aid for oral lesions because it is safe, accurate, convenient, and cost-effective.
口腔病变通常会导致诊断难题。细针穿刺细胞学检查（FNAC）是术前诊断口腔病变的一项重要诊断辅助手段。它不能替代组织病理学检查，而是对其起到补充作用。
对45例口腔病变患者进行了FNAC检查，所有病变均进行了组织病理学检查。使用Cameco注射器固定器（印度昌迪加尔的阿玛尔工业公司）中23至25号针头进行抽吸。
通过FNAC，我们诊断出22例良性病变、15例恶性病变和7例炎性病变，而有1例标本不足以进行诊断。有1例结果为假阴性，但无假阳性结果。FNAC的特异性和敏感性分别为95.45%和93.75%。FNAC对良性病变的诊断准确率为90.0%，对恶性病变为94.0%，对炎性病变为100%。
该检查方法无任何副作用或并发症。因此，FNAC可作为口腔病变可靠的诊断辅助手段，因为它安全、准确、便捷且具有成本效益。
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