Can Fam Physician. 1992 Nov;38:2656-66.
A review of Canadian surveillance data for the past decade indicates that the incidence of reported hepatitis B cases has increased despite the availability of safe and effective vaccine. Sexual transmission (particularly heterosexual transmission) is the major route of virus spread in North America. Because of this fact, and because immunization of selected high-risk groups has failed to control disease, universal immunization is the strategy of choice.
对加拿大过去十年的监测数据进行回顾表明,尽管有安全有效的疫苗,但报告的乙型肝炎病例发病率仍在上升。性传播(特别是异性传播)是病毒在北美的主要传播途径。基于这一事实,以及由于对选定的高危人群进行免疫接种未能控制疾病,普遍免疫接种是首选策略。