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[骨骼肌组织工程中支架材料的研究进展]

[Research progress of scaffold materials in skeletal muscle tissue engineering].

作者信息

Huang Weiyi, Liao Hua

机构信息

Department of Human Anatomy, Southern Medical University, Guangzhou Guangdong 510515, PR China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010 Nov;24(11):1386-91.

Abstract

OBJECTIVE

To review the current researches of scaffold materials for skeletal muscle tissue engineering, to predict the development trend of scaffold materials in skeletal muscle tissue engineering in future.

METHODS

The related literature on skeletal muscle tissue engineering, involving categories and properties of scaffold materials, preparative technique and biocompatibility, was summarized and analyzed.

RESULTS

Various scaffold materials were used in skeletal muscle tissue engineering, including inorganic biomaterials, biodegradable polymers, natural biomaterial, and biomedical composites. According to different needs of the research, various scaffolds were prepared due to different biomaterials, preparative techniques, and surface modifications.

CONCLUSION

The development trend and perspective of skeletal muscle tissue engineering are the use of composite materials, and the preparation of composite scaffolds and surface modification according to the specific functions of scaffolds.

摘要

目的

综述目前骨骼肌组织工程支架材料的研究情况,预测未来骨骼肌组织工程支架材料的发展趋势。

方法

总结并分析了骨骼肌组织工程的相关文献,内容涉及支架材料的类别与特性、制备技术及生物相容性。

结果

骨骼肌组织工程中使用了多种支架材料,包括无机生物材料、可降解聚合物、天然生物材料及生物医学复合材料。根据研究的不同需求,因生物材料、制备技术及表面修饰的不同而制备出了各种支架。

结论

骨骼肌组织工程的发展趋势及前景是使用复合材料,根据支架的特定功能制备复合支架并进行表面修饰。

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