National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand.
J Nat Prod. 2011 Feb 25;74(2):300-2. doi: 10.1021/np100873t. Epub 2011 Jan 12.
A novel 20-norpimarane glucoside, xylopimarane (1), together with the known sphaeropsidin C (2) and clonostachydiol (3), was isolated from the fungus Xylaria sp. BCC 4297. Compound 1 exhibited cytotoxicity to cancer cell lines KB, MCF-7, and NCI-H187 with respective IC(50) values of 1.0, 13, and 65 μM.
从真菌 Xylaria sp. BCC 4297 中分离得到了一种新的 20-降诺林烷葡萄糖苷，即罗汉松烷（1），以及已知的贝壳杉烯 C（2）和克隆司他醇（3）。化合物 1 对癌细胞系 KB、MCF-7 和 NCI-H187 表现出细胞毒性，其 IC50值分别为 1.0、13 和 65 μM。
