Qingdao Insitute of Bioenergy & Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shangdong Province, China 266101.
Org Lett. 2011 Feb 18;13(4):709-11. doi: 10.1021/ol102957c. Epub 2011 Jan 13.
2-Benzoylbenzoyl azides undergo facile cyclization under acidic conditions to give substituted dibenzo[b,f][1,5]-diazocines in good yields. This approach shortens the synthetic steps toward these compounds as compared with conventional methods. The mechanism of the diazocine synthesis is assumed to proceed by an unprecedented intermolecular [2 + 2] cyclization.
2-苯甲酰基苯甲酰叠氮化物在酸性条件下容易环化，以高收率生成取代的二苯并[b,f][1,5]二氮杂环辛烷。与传统方法相比，这种方法缩短了合成这些化合物的步骤。假定二氮杂环辛烷的合成机制是通过前所未有的分子间[2 + 2]环化进行的。
