使用单个物镜实现各向同性衍射极限聚焦。

Isotropic diffraction-limited focusing using a single objective lens.

机构信息

Institut Fresnel, CNRS, Aix-Marseille Université, Ecole Centrale Marseille, Campus de St Jérôme, 13013 Marseille, France.

出版信息

Phys Rev Lett. 2010 Nov 12;105(20):203903. doi: 10.1103/PhysRevLett.105.203903.

DOI:10.1103/PhysRevLett.105.203903

PMID:21231235

Abstract

Focusing a light beam through a lens produces an anisotropic spot elongated along the optical axis, because the light comes from only one side of the focal point. Using the time-reversal concept, we show that isotropic focusing can be realized by placing a mirror after the focal point and shaping the incident beam. This idea is applied to confocal microscopy and brings about a dramatic improvement of the axial resolution.

摘要

通过透镜聚焦光束会产生一个各向异性的光斑，该光斑沿光轴拉长，因为光线仅来自焦点的一侧。利用时间反演的概念，我们证明通过在焦点之后放置一面镜子并对入射光束进行整形，可以实现各向同性聚焦。这个想法应用于共焦显微镜，并带来了轴向分辨率的显著提高。