J. Koudy Williams is at the Comparative Medicine Clinical Research Center, Bowman Gray School of Medicine, Winston-Salem, NC, USA.
Trends Cardiovasc Med. 1996 Feb;6(2):53-7. doi: 10.1016/1050-1738(96)00008-4.
Vasa vasorum provide an important source of nutrition to arteries and veins. In normal arteries, vasa vasorum from the adventitia grow into the media of large arteries and veins and actively regulate blood flow to the wall of these vessels. In atherosclerotic arteries, vasa vasorum proliferate into the intima-media, where they provide nutrition to the thickened artery. These neovascular channels are thin-walled, however, and may contribute to intraplaque hemorrhage, plaque disruption, and mural thrombosis.
脉外膜血管为动脉和静脉提供重要的营养来源。在正常的动脉中,来自外膜的脉外膜血管向大动脉和大静脉的中膜生长,并积极调节这些血管壁的血流。在动脉粥样硬化的动脉中,脉外膜血管增生到内中膜,为增厚的动脉提供营养。然而,这些新生血管通道壁薄,可能导致斑块内出血、斑块破裂和壁血栓形成。