Can Fam Physician. 1990 Mar;36:543-614.
The prevention of post-menopausal osteoporosis is a challenge for primary care physicians. Recently available technology to determine bone density can help determine whether intervention other than dietary calcium recommendations and an exercise program is appropriate. Estrogen replacement therapy can be used for post-menopausal women who have no contra-indications. The use of concomitant progestational agents in a cyclic fashion or with a low-dose continuous regimen reduces the risk of endometrial malignancy. In the future new investigational agents that modulate bone turnover could be recommended.
预防绝经后骨质疏松症是初级保健医生面临的一个挑战。最近可用于确定骨密度的技术有助于确定是否需要进行除饮食钙推荐和运动方案以外的干预措施。对于没有禁忌症的绝经后妇女，可以使用雌激素替代疗法。采用周期性或低剂量连续方案使用伴随孕激素制剂可降低子宫内膜恶变的风险。未来可能会推荐新的调节骨转换的研究性药物。
