Département de chirurgie, institut universitaire de la face et du cou, Centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2011 Apr;128(2):47-51. doi: 10.1016/j.anorl.2010.12.001. Epub 2011 Jan 14.
To evaluate the reliability of free-flap head and neck reconstruction in the elderly.
All patients who underwent free-flap head and neck reconstruction in our institution between 2000 and 2010 were included in this retrospective study. In all, 418 patients (301 men and 117 women) were enrolled, including 95 patients aged 70 years or older (mean age=60.2±11.6 years). The impact of age on free-flap failure and local and general complication rates was assessed on univariate and multivariate analysis.
Advanced age had no impact on free-flap failure and local complications rate but was correlated with a higher risk of general complications (multivariate analysis: P=0.007). A high level of comorbidity also had a significant impact on the general complications rate (multivariate analysis: P=0.001). Patients who underwent circular total pharyngolaryngectomy showed elevated risk of free-flap failure (P=0.005) and local complications (P=0.001) on multivariate analysis.
Free-flap reconstruction of the head and neck is safe and reliable in the elderly. Nevertheless, meticulous patient selection, mainly based on the level of comorbidity, is necessary.
评估老年人游离皮瓣头颈部重建的可靠性。
本回顾性研究纳入了 2000 年至 2010 年期间在我院行游离皮瓣头颈部重建的所有患者。共纳入 418 例患者(301 名男性和 117 名女性),其中 95 例患者年龄≥70 岁(平均年龄=60.2±11.6 岁)。单因素和多因素分析评估了年龄对游离皮瓣失败和局部及总体并发症发生率的影响。
高龄对游离皮瓣失败和局部并发症发生率无影响,但与总体并发症发生率较高相关(多因素分析:P=0.007)。较高的合并症水平也对总体并发症发生率有显著影响(多因素分析:P=0.001)。多因素分析显示,行环状全咽及喉切除术的患者游离皮瓣失败(P=0.005)和局部并发症(P=0.001)的风险增加。
游离皮瓣重建头颈部在老年人中是安全可靠的。然而,需要进行仔细的患者选择,主要基于合并症的水平。