Breunung Lea, Roberts Mike
Department of General Medicine, Darent Valley Hospital, Dartford.
Br J Hosp Med (Lond). 2011 Jan;72(1):17-8, 20-1. doi: 10.12968/hmed.2011.72.1.17.
Chronic obstructive pulmonary disease is a systemic disease that includes significant adverse effects on muscle function, with varied changes to the structure and metabolism of the peripheral muscles. This review evaluates the evidence for the mechanisms that mediate these changes and the significance of the diminished muscle function.
慢性阻塞性肺疾病是一种全身性疾病,对肌肉功能有显著的不良影响,外周肌肉的结构和代谢会发生多种变化。本综述评估了介导这些变化的机制的证据以及肌肉功能减退的意义。