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处于单光子计数(SPC)模式下的固态X射线图像增强器(SSXII)。

The Solid State X-ray Image Intensifier (SSXII) in Single Photon Counting (SPC) mode.

作者信息

Kuhls-Gilcrist Andrew, Jain Amit, Bednarek Daniel R, Rudin Stephen

机构信息

University at Buffalo (State University of New York), Toshiba Stroke Research Center, 3435 Main St., Buffalo, NY USA 14214.

出版信息

Proc SPIE Int Soc Opt Eng. 2010 Mar 22;7622(76221P). doi: 10.1117/12.843785.

Abstract

The new Solid State X-Ray Image Intensifier (SSXII) has the unique ability to operate in single photon counting (SPC) mode, with improved resolution, as well as in traditional energy integrating (EI) mode. The SSXII utilizes an electron-multiplying CCD (EMCCD), with an effective pixel size of 32μm, which enables variable signal amplification (up to a factor of 2000) prior to digital readout, providing very high-sensitivity capabilities. The presampled MTF was measured in both imaging modes using the standard angulated-slit method. A measured detector entrance exposure of 24μR per frame was used to provide approximately 0.8 interaction events per pixel in the 10μm-wide slit area. For demonstration purposes, a simple thresholding technique was used to localize events in SPC mode and a number of such frames were summed to provide an image with the same total exposure used for acquiring the EI image. The MTF for SPC mode, using a threshold level of 15% of the maximum 12-bit signal and 95% of the expected events, and for EI mode (in parentheses) was 0.67 (0.20), 0.37 (0.07), 0.20 (0.03), and 0.11 (0.01) at 2.5, 5, 7.5, and 10 cycles/mm, respectively. Increasing the threshold level resulted in a corresponding increase in the measured SPC MTF and a lower number of detected events, indicating a tradeoff between resolution and count efficiency is required. The SSXII in SPC mode was shown to provide substantial improvements in resolution relative to traditional EI mode, which should benefit applications that have demanding spatial resolution requirements, such as mammography.

摘要

新型固态X射线图像增强器(SSXII)具有独特的能力,既能在单光子计数(SPC)模式下运行,具备更高的分辨率,也能在传统的能量积分(EI)模式下运行。SSXII采用电子倍增电荷耦合器件(EMCCD),有效像素尺寸为32μm,这使得在数字读出之前能够进行可变信号放大(放大倍数高达2000),具备非常高的灵敏度。使用标准的成角度狭缝法在两种成像模式下测量了预采样调制传递函数(MTF)。每帧24μR的探测器入口曝光量用于在10μm宽的狭缝区域每个像素提供约0.8次相互作用事件。为了演示目的,在SPC模式下使用简单的阈值技术来定位事件,并对多个这样的帧进行求和,以提供与获取EI图像所用总曝光量相同的图像。SPC模式下的MTF,使用最大12位信号的15%和预期事件的95%作为阈值水平,EI模式下(括号内)的MTF在2.5、5、7.5和10周期/毫米时分别为0.67(0.20)、0.37(0.07)、0.20(0.03)和0.11(0.01)。提高阈值水平会导致测量的SPC MTF相应增加,同时检测到的事件数量减少,这表明在分辨率和计数效率之间需要进行权衡。结果表明,与传统EI模式相比,处于SPC模式的SSXII在分辨率方面有显著提高,这将有利于对空间分辨率有严格要求的应用,如乳腺摄影。

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