Kuhls Andrew T, Yadava Girijesh, Patel Vikas, Bednarek Daniel R, Rudin Stephen
University at Buffalo (State University of New York), Toshiba Stroke Research Center, 3435 Main St., Buffalo, NY USA 14214.
Proc SPIE Int Soc Opt Eng. 2007;6510(1):65101C. doi: 10.1117/12.713140.
A new high-resolution, high-sensitivity, low-noise x-ray detector based on EMCCDs has been developed. The EMCCD detector module consists of a 1kx1k, 8μm pixel EMCCD camera coupled to a CsI(Tl) scintillating phosphor via a fiber optic taper (FOT). Multiple modules can be used to provide the desired field-of-view (FOV). The detector is capable of acquisitions over 30fps. The EMCCD's variable gain of up to 2000x for the pixel signal enables high sensitivity for fluoroscopic applications. With a 3:1 FOT, the detector can operate with a 144μm effective pixel size, comparable to current flat-panel detectors. Higher resolutions of 96 and 48μm pixel size can also be achieved with various binning modes. The detector MTFs and DQEs were calculated using a linear-systems analysis. The zero frequency DQE was calculated to be 59% at 74 kVp. The DQE for the 144μm pixel size was shown to exhibit quantum-noise limited behavior down to ~0.1μR using a conservative 30x gain. At this low exposure, gains above 30x showed limited improvements in DQE suggesting such increased gains may not be necessary. For operation down to 48μm pixel sizes, the detector instrumentation noise equivalent exposure (INEE), defined as the exposure where the instrumentation noise equals the quantum-noise, was <0.1μR for a 20x gain. This new technology may provide improvements over current flat-panel detectors for applications such as fluoroscopy and angiography requiring high frame rates, resolution, dynamic range and sensitivity while maintaining essentially no lag and very low INEE. Initial images from a prototype detector are also presented.
一种基于电子倍增电荷耦合器件(EMCCD)的新型高分辨率、高灵敏度、低噪声X射线探测器已被研发出来。该EMCCD探测器模块由一个1kx1k、8μm像素的EMCCD相机组成,通过光纤锥(FOT)与碘化铯(铊)闪烁磷光体相连。多个模块可用于提供所需的视场(FOV)。该探测器能够以超过30帧/秒的速度进行采集。EMCCD对像素信号高达2000倍的可变增益使其在荧光透视应用中具有高灵敏度。使用3:1的光纤锥时,该探测器可在144μm的有效像素尺寸下运行,与当前的平板探测器相当。通过各种合并模式还可实现96μm和48μm像素尺寸的更高分辨率。探测器的调制传递函数(MTF)和量子探测效率(DQE)使用线性系统分析进行了计算。在74 kVp时,零频率DQE计算为59%。对于144μm像素尺寸的探测器,使用保守的30倍增益时,其DQE在低至约0.1μR时表现出量子噪声受限行为。在这种低曝光情况下,高于30倍的增益在DQE方面的改善有限,这表明这种增加的增益可能没有必要。对于低至48μm像素尺寸的操作,探测器的仪器噪声等效曝光(INEE)(定义为仪器噪声等于量子噪声时的曝光)在20倍增益时<0.1μR。这项新技术可能比当前的平板探测器在荧光透视和血管造影等应用中有所改进,这些应用需要高帧率、分辨率、动态范围和灵敏度,同时基本没有滞后且仪器噪声等效曝光非常低。还展示了原型探测器的初始图像。