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2000 - 2003年以色列北部皮肤利什曼病疫情的地理与流行病学分析

Geographic and epidemiologic analysis of the cutaneous Leishmaniasis outbreak in northern Israel, 2000-2003.

作者信息

Vinitsky Olga, Ore Liora, Habiballa Hamza, Cohen-Dar Michal

机构信息

Ministry of Health - Northern District, Northern District, Nazareth Illit, Israel.

出版信息

Isr Med Assoc J. 2010 Nov;12(11):652-6.

PMID:21243862
Abstract

BACKGROUND

The incidence of cutaneous leishmaniasis in northern Israel began to rise in 2000, peaking at 41.0 per 100,000 in the Kinneret subdistrict during the first half of 2003.

OBJECTIVES

To examine the morbidity rates of CL in northern Israel during the period 1999-2003, which would indicate whether new endemic areas were emerging in this district, and to identify suspicious hosts.

METHODS

The demographic and epidemiologic data for the reported cases (n=93) were analyzed using the GIS and SPSS software, including mapping habitats of suspicious hosts and localizing sites of infected sand flies.

RESULTS

The maximal incidence rate in the district was found in the city Tiberias in 2003: 62.5/100,000 compared to 0-1.5/100,000 in other towns. The cases in Tiberias were concentrated on the peripheral line of two neighborhoods, close to the habitats of the rock hyraxes. Sand flies infected with Leishmania tropica were captured around the residence of those affected. Results of polymerase chain reaction were positive for Leishmania tropica in 14 of 15 tested patients.

CONCLUSIONS

A new endemic CL area has emerged in Tiberias. The most suspicious reservoir of the disease is the rock hyrax.

摘要

背景

以色列北部皮肤利什曼病的发病率自2000年开始上升,2003年上半年在基尼烈分区达到每10万人41.0例的峰值。

目的

研究1999 - 2003年期间以色列北部皮肤利什曼病的发病率,以确定该地区是否出现新的流行区,并识别可疑宿主。

方法

使用GIS和SPSS软件分析报告病例(n = 93)的人口统计学和流行病学数据,包括绘制可疑宿主的栖息地地图以及确定受感染白蛉的地点。

结果

该地区发病率最高的是2003年的提比里亚斯市:每10万人62.5例,而其他城镇为每10万人0 - 1.5例。提比里亚斯的病例集中在两个社区的周边地带,靠近岩蹄兔的栖息地。在患者住所周围捕获了感染热带利什曼原虫的白蛉。15名受试患者中有14人的聚合酶链反应结果显示热带利什曼原虫呈阳性。

结论

提比里亚斯出现了一个新的皮肤利什曼病流行区。该病最可疑的宿主是岩蹄兔。

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