Fassoulaki A, Andreopoulou K, Saleh M, Kitharitzi D
Department of Anesthesia, St. Savas Hospital, Athens, Greece.
Acta Anaesthesiol Belg. 1990;41(3):281-6.
The cardiovascular and metabolic responses to oral and nasal intubation of the trachea were studied in 24 unpremedicated patients, free from cardiovascular disease and scheduled for excision of breast lump. Systolic blood pressure (SBP) and heart rate (HR) were recorded with a Dinamap 1846 SX before and at 1 minute intervals for 10 minutes following oral (group A = 12 patients) or nasal (group B = 12 patients) intubation. Oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured at 1 minute intervals for 10 minutes following tracheal intubation using the Engström Metabolic Computer and an infrared CO2 analyzer. No significant differences in SBP and HR preinduction and postintubation values were found between the two groups. Both oral and nasal intubation were associated with significant increases in VO2 (p less than 0.001 and p less than 0.001 respectively), VCO2 (p less than 0.001 and p less than 0.001), SBP (p less than 0.001 and p less than 0.001) and HR (p less than 0.001 and p less than 0.001). Nasal intubation of the trachea was associated with significantly higher VO2 (p less than 0.05-0.01) and VCO2 (p less than 0.05-0.001) values when compared with the VO2 and VCO2 values following oral intubations.
对24例未接受术前用药、无心血管疾病且计划进行乳腺肿块切除术的患者，研究了经口和经鼻气管插管时的心血管及代谢反应。在经口插管组（A组 = 12例患者）或经鼻插管组（B组 = 12例患者）前及插管后10分钟内，每隔1分钟用Dinamap 1846 SX记录收缩压（SBP）和心率（HR）。使用Engström代谢计算机和红外二氧化碳分析仪，在气管插管后10分钟内每隔1分钟测量耗氧量（VO2）和二氧化碳产生量（VCO2）。两组间诱导前和插管后SBP及HR值无显著差异。经口和经鼻插管均与VO2（分别为p < 0.001和p < 0.001）、VCO2（p < 0.001和p < 0.001）、SBP（p < 0.001和p < 0.001）及HR（p < 0.001和p < 0.001）的显著升高相关。与经口插管后的VO2和VCO2值相比，经鼻气管插管时的VO2（p < 0.05 - 0.01）和VCO2（p < 0.05 - 0.001）值显著更高。
