Department of Psychology, Kent State University, Kent Hall, Kent, Ohio 44242, USA.
Int J Neurosci. 2011 Apr;121(4):218-23. doi: 10.3109/00207454.2010.546537. Epub 2011 Jan 19.
Exercise has been shown to have positive effects on the brain and cognition in healthy older adults, though no study has directly examined possible cognitive benefits of formal exercise programs in persons with mild cognitive impairment (MCI) living in structured facilities. Thirty-one participants completed neuropsychological testing and measures of cardiovascular fitness at baseline and after 6 months of a structured exercise program that included aerobic and resistance training. While exercise improved cardiovascular fitness in persons with MCI, there was no improvement in cognitive function. Rather, MCI patients in this sample declined in performance on several tests sensitive to Alzheimer's disease. Examined in the context of past work, it appears exercise may be beneficial prior to the onset of MCI, though less helpful after its onset.
运动已被证明对健康老年人的大脑和认知能力有积极影响，但尚无研究直接考察生活在结构化设施中的轻度认知障碍（MCI）患者参加正规运动项目可能带来的认知益处。31 名参与者在基线时和经过 6 个月的结构化运动项目（包括有氧运动和抗阻训练）后完成了神经心理学测试和心血管健康指标的测量。虽然运动改善了 MCI 患者的心血管健康，但他们的认知功能没有改善。相反，该样本中的 MCI 患者在几项对阿尔茨海默病敏感的测试中的表现有所下降。结合过去的研究来看，运动似乎在 MCI 发病前有益，但在发病后则帮助较小。
