氟卡尼中毒
Flecainide intoxication.
作者信息
Levine B, Chute D, Caplan Y H
机构信息
Office of the Chief Medical Examiner, State of Maryland, Baltimore, Maryland 21201.
出版信息
J Anal Toxicol. 1990 Sep-Oct;14(5):335-6. doi: 10.1093/jat/14.5.335.
A fatal case attributed to flecainide intoxication is presented. Quantitation was by capillary gas chromatography with nitrogen-phosphorus detection. The flecainide concentration in the blood was 13 mg/L as compared to a therapeutic range in serum of 0.2-1.0 mg/L. Flecainide concentrations in other specimens were as follows: bile, 160 mg/L; urine, 54 mg/L; vitreous humor, 7.4 mg/L; liver, 180 mg/kg; kidney, 74 mg/kg; and stomach contents, 120 mg.
本文报告了一例因氟卡尼中毒致死的病例。采用带氮磷检测的毛细管气相色谱法进行定量分析。血液中氟卡尼浓度为13mg/L，而血清治疗浓度范围为0.2 - 1.0mg/L。其他样本中的氟卡尼浓度如下：胆汁，160mg/L；尿液，54mg/L；玻璃体液，7.4mg/L；肝脏，180mg/kg；肾脏，74mg/kg；胃内容物，120mg。
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