Luo Wen-Zheng, Zhang Qing-Zhong, Lai Xin-Sheng
Rehabilitation Department, Affiliated Huai'an First Hospital of Nanjing Medical University, Huai'an 223300, China.
Zhongguo Zhen Jiu. 2010 Nov;30(11):899-903.
To compare the therapeutic effects of insomnia accompanied with depressive disorders treated by acupuncture of relieving depression and regulating mind and oral administration of Trazodone.
Sixty-five cases were randomly divided into a acupuncture group (33 cases) and western medication group (32 cases). In acupuncture group, Shenmen (HT 7), Baihui (CV 20), Hegu (LI 4) and Taichong (LR 3) were selected. In western medication group, Trazodone was applied with oral administration for 4 weeks. The curative effect comparison was carried on by Pittsburgh Sleep Quality Index (PSQI), Self-Rating Depression Scale (SDS), and Side Effect Rating Scale (SERS) of Asberg.
The cured and markedly effective rate of 72.7% (24/33)in acupuncture group was superior to that of 46.8% (15/32) in western medication group; after treatment, the scores of all items and the total cumulative scores of PSQI and SDS of both groups were reduced (P < 0.01, P < 0.05), of which, the sleep quality and daytime function evaluation in acupuncture group reduced more obviously than those in western medication group (both P < 0.05); the SERS scores of Asberg in western medication group were higher than those in acupuncture group.
Acupuncture treatment of relieving depression and regulating mind is superior to Trazodone with oral administration for sleep quality and daytime function, with milder adverse reactions.
比较针刺解郁调神法与口服曲唑酮治疗伴发抑郁障碍的失眠症的疗效。
将65例患者随机分为针刺组(33例)和西药组(32例)。针刺组选取神门(HT 7)、百会(CV 20)、合谷(LI 4)、太冲(LR 3);西药组口服曲唑酮,疗程4周。采用匹兹堡睡眠质量指数(PSQI)、自评抑郁量表(SDS)及阿氏不良反应量表(SERS)进行疗效比较。
针刺组治愈率和显效率为72.7%(24/33),优于西药组的46.8%(15/32);治疗后两组PSQI、SDS各条目及总分均降低(P<0.01,P<0.05),其中针刺组睡眠质量及日间功能改善较西药组明显(均P<0.05);西药组阿氏不良反应量表评分高于针刺组。
针刺解郁调神法治疗伴发抑郁障碍的失眠症在睡眠质量及日间功能方面优于口服曲唑酮,且不良反应较轻。