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与对照组相比，针刺治疗抑郁症相关失眠的疗效：一项系统评价与Meta分析

The Efficacy of Acupuncture for Treating Depression-Related Insomnia Compared with a Control Group: A Systematic Review and Meta-Analysis.

作者信息

Dong Bo, Chen Zeqin, Yin Xuan, Li Danting, Ma Jie, Yin Ping, Cao Yan, Lao Lixing, Xu Shifen

机构信息

Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai, Shanghai University of TCM, Shanghai 200071, China.

School of Medicine, Nanchang University, Jiangxi 330031, China.

出版信息

Biomed Res Int. 2017;2017:9614810. doi: 10.1155/2017/9614810. Epub 2017 Feb 14.

DOI:10.1155/2017/9614810
PMID:28286776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5329663/
Abstract

To evaluate the effectiveness of acupuncture as monotherapy and as an alternative therapy in treating depression-related insomnia. Seven databases were searched starting from 1946 to March 30, 2016. Randomized-controlled trials of adult subjects (18-75 y) who had depression-related insomnia and had received acupuncture. 18 randomized-controlled clinical trials (RCTs) were introduced in this meta-analysis. The findings determined that the acupuncture treatment made significant improvements in PSQI score (MD = -2.37, 95% CI -3.52 to -1.21) compared with Western medicine. Acupuncture combined with Western medicine had a better effect on improving sleep quality (MD = -2.63, 95% CI -4.40 to -0.86) compared with the treatment of Western medicine alone. There was no statistical difference (MD = -2.76, 95% CI -7.65 to 2.12) between acupuncture treatment and Western medicine towards improving the HAMD score. Acupuncture combined with Western medicine (MD = -5.46, CI -8.55 to -2.38) had more effect on improving depression degree compared with the Western medicine alone. . This systematic review indicates that acupuncture could be an alternative therapy to medication for treating depression-related insomnia.

摘要

评估针刺疗法作为单一疗法以及作为替代疗法治疗抑郁症相关失眠的有效性。检索了从1946年至2016年3月30日的七个数据库。纳入了患有抑郁症相关失眠且接受针刺治疗的成年受试者（18 - 75岁）的随机对照试验。本荟萃分析纳入了18项随机对照临床试验（RCT）。研究结果表明，与西药相比，针刺治疗在匹兹堡睡眠质量指数（PSQI）评分方面有显著改善（MD = -2.37，95%CI -3.52至-1.21）。与单纯西药治疗相比，针刺联合西药在改善睡眠质量方面效果更好（MD = -2.63，95%CI -4.40至-0.86）。针刺治疗与西药在改善汉密尔顿抑郁量表（HAMD）评分方面无统计学差异（MD = -2.76，95%CI -7.65至2.12）。与单纯西药相比，针刺联合西药在改善抑郁程度方面效果更显著（MD = -5.46，CI -8.55至-2.38）。本系统评价表明，针刺疗法可作为治疗抑郁症相关失眠的药物替代疗法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90c3/5329663/d65171e78716/BMRI2017-9614810.010.jpg
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