Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London SW7 2AZ, UK.
Université de Paris-Sud XI, USC INRA EA 4043, Faculté de Pharmacie, Châtenay-Malabry Cedex, France.
J Med Microbiol. 2011 Aug;60(Pt 8):1225-1228. doi: 10.1099/jmm.0.028472-0. Epub 2011 Jan 20.
Strains of Clostridium difficile produce a number of surface-localized proteins, including the S-layer proteins (SLPs) and other proteins that have suspected roles in pathogenesis. During the Third International C. difficile Symposium (Bled, Slovenia, September 2010) discussions were held on standardization of nomenclature. Gene designations were proposed for the large family of cell wall proteins that are paralogues of the SLP and contain putative cell wall binding motifs. This paper summarizes the agreed nomenclature, which we hope will be used by research groups currently active in the field.
艰难梭菌产生许多表面定位蛋白，包括 S 层蛋白（SLP）和其他疑似在发病机制中起作用的蛋白。在第三届艰难梭菌国际研讨会（2010 年 9 月，斯洛文尼亚布莱德）上，就命名法标准化进行了讨论。针对 SLP 的同源物细胞壁蛋白大家族提出了基因命名，这些蛋白包含潜在的细胞壁结合基序。本文总结了商定的命名法，我们希望该命名法将被目前活跃于该领域的研究小组使用。
