Noble M A, Barteluk R L, Farquhar D J, Smith R P
Can Fam Physician. 1988 Aug;34:1687-92.
The prevalence of chlamydia trachomatis was investigated over a two-year period in a population of women university students attending a student health clinic for routine pelvic examination or for a gynecologic complaint. Direct immunofluorescence slide test was used to determine the presence of C. trachomatis. The overall prevalence rates for the two-years periods studied were 8.2% and 7.1%. When women who had symptoms of a urogenital infection were compared to women who were asymptomatic, it was found that symptomatic women were more likely to have C. trachomatis in the cervix. To determine whether women with positive cases showed differences in appearance of the cervix, method of contraception, or other organisms colonizing the vagina, the cases were matched with two controls, and a retrospective chart review was performed. The cases were more likely to have cervicitis and to be culture positive with gardnerella vaginalis, and they were less likely to have used condoms for contraception. In the two periods studied, the carriage rates for asymptomatic cases were 6% and 5%. Fifty-eight per cent of all positive cases were asymptomatic. If this organism is to be eradicated from college-women populations, all women attending for a urogenital infection should be screened, and women attending for routine annual examinations should be screened if there is a clinical indication.
在两年时间里，对前往学生健康诊所进行常规盆腔检查或因妇科疾病就诊的女大学生群体进行了沙眼衣原体患病率调查。采用直接免疫荧光玻片试验来确定沙眼衣原体的存在。所研究的两年期间的总体患病率分别为8.2%和7.1%。将有泌尿生殖系统感染症状的女性与无症状女性进行比较时，发现有症状的女性宫颈中更易感染沙眼衣原体。为了确定阳性病例的女性在宫颈外观、避孕方法或阴道中定植的其他微生物方面是否存在差异，将病例与两名对照进行匹配，并进行回顾性病历审查。病例更易患宫颈炎且阴道加德纳菌培养呈阳性，且她们使用避孕套避孕的可能性较小。在所研究的两个时期，无症状病例的携带率分别为6%和5%。所有阳性病例中有58%无症状。如果要从大学女性群体中根除这种微生物，所有因泌尿生殖系统感染就诊的女性都应接受筛查，而因年度常规检查就诊的女性如有临床指征也应接受筛查。
