Leclerc A, Frost E, Collet M, Goeman J, Bedjabaga L
Centre International de Recherches Médicales de Franceville, Gabon.
Genitourin Med. 1988 Oct;64(5):308-11. doi: 10.1136/sti.64.5.308.
Samples from 218 men with urethritis, 517 women with pelvic pain or pelvic pain and vaginal discharge, 218 women consulting for infertility, and 598 postpartal women were screened for Chlamydia trachomatis by culture and direct immunofluorescence. Chlamydiae were detected in 18% (39/218) of the men, 18% (45/252) of women with vaginal discharge, 14% (38/265) of those with pelvic pain, 10% (21/218) of infertile, and 10% (59/598) of postpartal women. A chlamydial prevalence of 18% (41) was observed in 229 postpartal women aged under 21, whereas only 5% (10) of 360 postpartal women over 21 had C trachomatis. In the other clinical groups, an age related decrease in prevalence was noted in women over 25. The direct immunofluorescence test correlated well with culture. The small difference in isolation between symptomatic and postpartal women indicates that women in this population do not seek medical attention for chlamydial infections and expose themselves to chlamydial salpingitis and infertility.
对218名尿道炎男性患者、517名有盆腔疼痛或盆腔疼痛伴阴道分泌物的女性患者、218名因不孕症前来咨询的女性患者以及598名产后女性的样本进行培养和直接免疫荧光法检测沙眼衣原体。在男性中,沙眼衣原体检出率为18%(39/218);有阴道分泌物的女性中为18%(45/252);有盆腔疼痛的女性中为14%(38/265);不孕女性中为10%(21/218);产后女性中为10%(59/598)。在229名21岁以下的产后女性中,沙眼衣原体患病率为18%(41例),而在360名21岁以上的产后女性中,只有5%(10例)感染了沙眼衣原体。在其他临床组中,25岁以上女性的患病率呈年龄相关性下降。直接免疫荧光试验与培养结果相关性良好。有症状女性和产后女性在衣原体分离方面的微小差异表明,该人群中的女性衣原体感染后未寻求医疗帮助,从而使自己面临衣原体性输卵管炎和不孕症的风险。