Stockley H L, Bennett A
J Pharm Pharmacol. 1977 Sep;29(9):533-7. doi: 10.1111/j.2042-7158.1977.tb11390.x.
In human taenia coli electrical field stimulation after cholinergic blockade excited mainly non-adrenergic inhibitory nerves. Adrenergic relaxations during stimulation were demonstrated only with short electrical pulses at high frequencies or with ganglion stimulants. Reduction by tetrodotoxin of relaxations to indirectly acting sympathomimetics supports the histochemical finding that colonic adrenergic nerves are mainly preganglionic, and possibly synapse with non-adrenergic inhibitory nerves. When the latter undergo direct maximal stimulation, responses to adrenergic nerve excitation are masked.
在人结肠带中，胆碱能阻断后进行电场刺激主要兴奋非肾上腺素能抑制神经。仅在高频短电脉冲或使用神经节兴奋剂时，才会出现刺激期间的肾上腺素能舒张。河豚毒素减弱对间接作用拟交感神经药的舒张反应，这支持了组织化学研究结果，即结肠肾上腺素能神经主要是节前神经，并且可能与非肾上腺素能抑制神经形成突触。当后者受到直接最大刺激时，对肾上腺素能神经兴奋的反应会被掩盖。
