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非体外循环下主动脉弓杂交去分支和胸主动脉腔内修复术治疗复杂慢性A型主动脉夹层再手术患者:一份关键报告

Hybrid debranching and TEVAR of the aortic arch off-pump, in re-do patients with complicated chronic type-A aortic dissections: a critical report.

作者信息

Brechtel Klaus, Kalender Günay, Stock Ulrich A, Wildhirt Stephen M

机构信息

Isar Heart Center, Munich, Germany.

出版信息

J Cardiothorac Surg. 2013 Sep 4;8:188. doi: 10.1186/1749-8090-8-188.

Abstract

BACKGROUND

Patients suffering from acute type A aortic dissection undergo replacement of the ascending aorta, the proximal hemiarch or complete aortic arch, depending on the extent of the individual pathology. In a subset of these treated patients, secondary pathologies of the distal anastomosis or the remaining distal part of the aorta occur. The treatment of these pathologies is challenging, requiring major surgical re-do procedures with aortic arch replacement under extracorporeal circulation and hypothermic circulatory arrest.

METHODS

We report our experience of five patients with complex aortic pathologies after previous aortic surgery treated with a single stage re-do hybrid procedure, consisting of bypass grafting of the supraaortic branches off-pump, stent graft placement for endovascular aortic repair (TEVAR) and surgical debranching of the aortic arch.

RESULTS

In all patients the surgical vascular grafts and stent grafts were deployed successfully, there were no intraoperative deaths. Four out of five patients were discharged from hospital in good clinical condition. One patient died postoperatively due to cardiac tamponade. In one patient a type I endoleak persisted leading to occlusion of a bypass branch requiring surgical revision at one year after debranching.

CONCLUSION

We discuss the prerequisites, all steps and potential pitfalls of this hybrid aortic arch replacement. The current procedure avoids cardiopulmonary bypass and circulatory arrest, which may benefit early patient outcome; however, patient and device selection plays a key role for immediate success and midterm outcomes. In addition, precise procedural planning and development of customized stents may help to develop this procedure into a true alternative for conventional aortic arch replacement.

摘要

背景

急性A型主动脉夹层患者需根据个体病变程度进行升主动脉、近端半弓或全主动脉弓置换。在这些接受治疗的患者中,一部分会出现远端吻合口或主动脉其余远端部分的继发性病变。这些病变的治疗具有挑战性,需要在体外循环和低温循环停搏下进行主动脉弓置换的大型再次手术。

方法

我们报告了5例先前接受主动脉手术后出现复杂主动脉病变的患者,采用单阶段再次手术杂交手术进行治疗的经验,该手术包括在非体外循环下对主动脉弓上分支进行旁路移植、放置血管内主动脉修复支架移植物(TEVAR)以及对主动脉弓进行手术去分支。

结果

所有患者的手术血管移植物和支架移植物均成功植入,无术中死亡。5例患者中有4例临床状况良好出院。1例患者术后因心脏压塞死亡。1例患者术后持续存在I型内漏,导致旁路分支闭塞,在去分支术后1年需要进行手术修复。

结论

我们讨论了这种杂交主动脉弓置换的前提条件、所有步骤和潜在陷阱。当前的手术避免了体外循环和循环停搏,这可能有利于患者的早期预后;然而,患者和器械的选择对即刻成功和中期预后起着关键作用。此外,精确的手术规划和定制支架的开发可能有助于将该手术发展成为传统主动脉弓置换的真正替代方案。

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