Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, North Mymms, Hatfield, Hertfordshire AL9 7TA.
Vet Rec. 2010 Oct 30;167(18):690-4. doi: 10.1136/vr.c5177.
A retrospective study of laminitis was carried out to identify risk factors associated with this disease on an East Anglian farm with approximately 1000 animals living in an area of 1000 acres. Medical records between January 1997 and May 2000 and between April 2005 and March 2008 were reviewed, and the age, sex, weight (kg), height (inches [in] and hands [H]) and weight-to-height ratio (kg/in) was recorded. The prevalence, incidence and seasonality of laminitis were determined and their relationship to the monthly temperature, rainfall and hours of sunshine was evaluated. Averaged over the six years, the highest prevalence (2.6 per cent) and incidence (16 cases/1000 animals) of laminitis occurred in May. The findings of a multivariate analysis revealed that females (P=0.007, odds ratio [OR] 1.46, 95 per cent confidence interval [CI] 1.1053 to 1.9646) and light animals (P ≤ 0.001, OR=0.995, 95 per cent CI =0.9932 to 0.9963) had the greatest risk of developing laminitis. A positive association was found between hours of sunshine and incidence (P=0.007, relative risk [RR] 1.009, 95 per cent CI 1.001 to 1.012) and prevalence (P=0.002, RR 1.008, 95 per cent CI 1.003 to 1.012) of laminitis. The data suggest that there is a relationship between season, sex of the animal and the development of laminitis.
一项关于蹄叶炎的回顾性研究旨在确定与东安格利亚一个拥有约 1000 头动物的 1000 英亩区域农场相关的该病的风险因素。回顾了 1997 年 1 月至 2000 年 5 月和 2005 年 4 月至 2008 年 3 月的医疗记录，并记录了动物的年龄、性别、体重（kg）、身高（英寸[in]和手[H]）和体重-身高比（kg/in）。确定了蹄叶炎的流行率、发病率和季节性，并评估了其与每月温度、降雨量和日照时间的关系。六年平均来看，蹄叶炎的最高流行率（2.6%）和发病率（16 例/1000 头动物）发生在 5 月。多变量分析的结果显示，雌性（P=0.007，优势比[OR]1.46，95%置信区间[CI]1.1053 至 1.9646）和轻体重动物（P≤0.001，OR=0.995，95%CI=0.9932 至 0.9963）患蹄叶炎的风险最大。发现日照时间与发病率（P=0.007，相对风险[RR]1.009，95%CI 1.001 至 1.012）和流行率（P=0.002，RR 1.008，95%CI 1.003 至 1.012）之间存在正相关关系。数据表明，季节、动物性别与蹄叶炎的发生之间存在关系。
