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[电针(EA)对大鼠急性实验性关节炎的治疗作用]

[Therapeutic effects of electroacupuncture (EA) on acute experimental arthritis in rats].

作者信息

Zhao F, Zhu L, Li Y

机构信息

Institute of Acupuncture, China Academy of Traditional Chinese Medicine, Beijing.

出版信息

Zhen Ci Yan Jiu. 1990;15(3):197-202.

PMID:2125879
Abstract

The dynamic changes of the pain thresholds (Heat-Withdrawal Latency, HWL and Stimulation-Vocalization Threshold, Voc) in the adjuvant-induced arthritic rats and the effects of EA on the pain thresholds, skin temperature and the circumference of the diseased ankle were observed. Both pain thresholds were obviously decreased in affected limbs in EA and control groups. But in the normal limbs, HWL decreased and Voc, no changed. In EA group, the ankle circumference and skin temperature were markedly lower than that in control group. The increase of the body weight was much more obvious than that in control group. Our experiment revealed that EA could not only increase the pain threshold, but also improve the pathological changes in the inflammation of the ankle, the mechanisms of the changes of the pain thresholds and the effects of EA in the arthritic rats were discussed.

摘要

观察佐剂诱导的关节炎大鼠疼痛阈值(热退缩潜伏期,HWL和刺激发声阈值,Voc)的动态变化以及电针对疼痛阈值、皮肤温度和患病踝关节周长的影响。电针组和对照组患侧肢体的两种疼痛阈值均明显降低。但在正常肢体中,HWL降低而Voc无变化。电针组踝关节周长和皮肤温度明显低于对照组。体重增加比对照组明显得多。我们的实验表明,电针不仅可以提高疼痛阈值,还可以改善踝关节炎症的病理变化,并讨论了疼痛阈值变化的机制以及电针在关节炎大鼠中的作用。

相似文献

1
[Therapeutic effects of electroacupuncture (EA) on acute experimental arthritis in rats].[电针(EA)对大鼠急性实验性关节炎的治疗作用]
Zhen Ci Yan Jiu. 1990;15(3):197-202.
2
[Effects of electroacupuncture on the immunoreactivity of focal cutaneous CB2 receptor positive cells in arthritis rats].[电针对关节炎大鼠局部皮肤CB2受体阳性细胞免疫反应性的影响]
Zhen Ci Yan Jiu. 2007 Feb;32(1):9-15.
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[Effects of electroacupuncture and manual acupuncture interventions on contents of serum inflammatory cytokines in rats with chronic adjuvant arthritis].[电针与手针干预对慢性佐剂性关节炎大鼠血清炎症细胞因子含量的影响]
Zhen Ci Yan Jiu. 2012 Aug;37(4):271-6.
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[Changes in responses of parafascicular nuclei during adjuvant-induced acute arthritis and effect of acupuncture in the rat].[佐剂诱导的大鼠急性关节炎期间束旁核反应的变化及针刺的影响]
Zhen Ci Yan Jiu. 1990;15(1):77-81, 29.
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[Study on the analgesic effect of acupuncture with opioid receptors agonist in induced arthritic rats].[阿片受体激动剂穴位注射对佐剂性关节炎大鼠的镇痛作用研究]
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[Relationship between the function of mast cells and acupuncture analgesia in adjuvant arthritis rats].[佐剂性关节炎大鼠肥大细胞功能与针刺镇痛的关系]
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[Effects of electroacupuncture at different frequencies on the nociceptive response and central contents of GABA and glutamic acid in arthritic rats].[不同频率电针对关节炎大鼠伤害性反应及中枢γ-氨基丁酸和谷氨酸含量的影响]
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[Effects of electroacupuncture on GDNF positive cell immunoreactivity in local dermal tissue of the inflammatory pain focus in the rat of adjuvant arthritis].[电针对佐剂性关节炎大鼠炎性疼痛病灶局部皮肤组织中胶质细胞源性神经营养因子阳性细胞免疫反应性的影响]
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