EMGO+ Institute and Department of Public and Occupational Health, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.
BMC Public Health. 2011 Jan 24;11(1):49. doi: 10.1186/1471-2458-11-49.
Overweight (Body Mass Index [BMI] ≥ 25 kg/m²) and obesity (BMI ≥ 30 kg/m²) are associated with increased cardiovascular risk, posing a considerable burden to public health. The main aim of this study was to investigate lifestyle intervention effects on cardiovascular risk factors in healthy overweight employees.
Participants were 276 healthy overweight employees (69.2% male; mean age 44.0 years [SD 9.2]; mean BMI 29.7 kg/m² [SD 3.1]). They were randomized to one of two intervention groups receiving a six month lifestyle intervention with behavior counseling by phone (phone group) or e-mail (Internet group), or to a control group receiving usual care. Body weight, height, waist circumference, sum of skinfolds, blood pressure, total cholesterol level and predicted aerobic fitness were measured at baseline, at 6 and at 24 months. Regression analyses included the 141 participants with complete data.
At 6 months a significant favorable effect on total cholesterol level (-0.2 mmol/l, 95%CI -0.5 to -0.0) was observed in the phone group and a trend for improved aerobic fitness (1.9 ml/kg/min, 95%CI -0.2 to 3.9) in the Internet group. At two years, favorable trends for body weight (-2.1 kg, 95%CI -4.4 to 0.2) and aerobic fitness (2.3 ml/kg/min, 95%CI -0.2 to 4.8) were observed in the Internet group.
The intervention effects were independent of the used communication mode. However short-term results were in favor of the phone group and long-term results in favor of the internet group. Thus, we found limited evidence for our lifestyle intervention to be effective in reducing cardiovascular risk in a group of apparently healthy overweight workers.
ISRCTN04265725.
超重（体重指数[BMI]≥25kg/m²）和肥胖（BMI≥30kg/m²）与心血管风险增加相关，对公共健康造成了相当大的负担。本研究的主要目的是调查健康超重员工生活方式干预对心血管危险因素的影响。
参与者为 276 名健康超重员工（69.2%为男性；平均年龄 44.0 岁[标准差 9.2]；平均 BMI 为 29.7kg/m²[标准差 3.1]）。他们被随机分为两组干预组，分别接受为期 6 个月的生活方式干预，通过电话（电话组）或电子邮件（互联网组）进行行为咨询，或作为对照组接受常规护理。在基线、6 个月和 24 个月时测量体重、身高、腰围、皮褶厚度总和、血压、总胆固醇水平和预测有氧适能。回归分析包括 141 名数据完整的参与者。
在 6 个月时，电话组总胆固醇水平显著降低（-0.2mmol/l，95%CI -0.5 至 -0.0），互联网组有氧适能有改善趋势（1.9ml/kg/min，95%CI -0.2 至 3.9）。在两年时，互联网组体重（-2.1kg，95%CI -4.4 至 0.2）和有氧适能（2.3ml/kg/min，95%CI -0.2 至 4.8）有改善趋势。
干预效果与所使用的沟通模式无关。然而，短期结果有利于电话组，长期结果有利于互联网组。因此，我们发现我们的生活方式干预在降低一群明显健康的超重工人的心血管风险方面的有效性证据有限。
ISRCTN04265725。
